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23. Al-Karadaghi, S., Ævarsson, A., Garber, M., Zheltonosova, J & Liljas, A.
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25. Unge, J., Al-Karadaghi, S., Eliseikina, I., Jonsson, B.-H., Nikonov, S., Garber,
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26. Al-Karadaghi, S., Hansson, M., Nikonov, S., Jönsson, B., Hederstdet, L. (1997).
Crystal structure of ferrochelatase - the terminal enzyme in heme biosynthesis. Structure 5, 1501-1510.
27. Nevskaya, N., Tishchenko, S., Nikulin, A., Al-Karadaghi, S., Liljas, A.,
Ehresmann, B., Ehresmann, C., Garber M. & Nikonov S.(1998). Crystal structure of ribosomal protein S8 from Thermus termophilus reveals a high degree of structural conservation of a specific RNA binding site. J. Mol. Biol. 279, 233-244.
28. Unge, J., Åberg, A., Al-Karadaghi, S., Nikulin, A., Nikonov, S., Davydova, N.,
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29. Ursby, T. Adinolfi, B.S., Al-Karadaghi, S., De Vendittis, E. & Buccini, V.
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30. Willows, R., Hansson, M., Beale, S.I. & Al-Karadaghi, S. (1999). Crystallisation
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31. Selmer, M., Al-Karadaghi, S., Kaji, A., Liljas A. (1999). Crystallisation and
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32. Selmer, M., Al-Karadaghi, S., Hirokawa, G., Kaji, A. & Liljas, A. (1999).
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33. Lecerof, D., Fodje, M., Hansson, A., Hansson, M. & Al-Karadaghi, S. (2000).
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34. Nevskaya, N., Tischenko, S., Fedorov, R., Al-Karadaghi, S., Liljas, A., Kraft, A.,
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35. Fedorov, R. V., Meshcheryakov, V. A., Gongadze, G. M., Fomenkova, N. P., Nevskaya, N. A., Selmer, M., Laurberg, M., Kristensen, O., Al-Karadaghi, S.,
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36. Fodje, M., Hansson, A., Hansson, M., Olsen, J. G., Gough, S., Willows, R. D.& Al-Karadaghi, S. (2001). Interplay between an AAA module and an integrin I
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38. Olsson, U., Billberg, A., Sjovall, S., Al-Karadaghi, S. & Hansson, M. (2002). In
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40. Lecerof, D., Fodje, M., León, R.A., Olsson, U., Hansson, A., Sigfridsson, E., Ryde, U, Hansson, M. & Al-Karadaghi, S. (2003). Metal binding to Bacillus
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41. Willows, R. D., Hansson, A., Birch, D., Al-Karadaghi, S. & Hansson, M. (2004).
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42. Lundell, A., Olin, A.I., Mörgelin, M., Al-Karadaghi, S., Aspberg, A.& Logan,
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43. Shipovskov, S., Karlberg, T., Fodje, M., Hansson, M., Reimann, C.T. & Al-
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mesoporphyrin by ferrochelatase: implications for the catalytic reaction
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44. Dufe, V.T., Luersen, K., Eschbach, M.L., Haider, N., Karlberg, T., Walter, R.D. & Al-Karadaghi, S. (2005). Cloning, expression, characterisation and three-
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45. Brodelius. M., Hiraiwa, M., Marttila, S., Al Karadaghi, S., Picaud, S. and E.
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tissues and in barley seeds. Phys. Plantarum 125, 405–418.
46. Norrman, M., Ståhl, K., Schluckebier, G. & Al-Karadaghi S. (2006)
Characterisation of insulin microcrystals by use of x-ray powder diffraction and
multivariate data analysis. J. Appl. Crystallogr. 39, 391–400.
47. Schagerlöf, U., Wilson, G., Hebert, H., Al-Karadaghi, S., & Hägerhäll, C.
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48. Karlberg, T., Schagerlöf, U., Gakh, O., Park, S., Ryde, U., Lindahl, M., Leath, K., Garman, E., Isaya, G. & Al-Karadaghi, S. (2006). Structure of frataxin
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49. Sirijovski, N, Olsson, U, Lundqvist, J, Al-Karadaghi, S, Willows, RD &
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51. Hansson, M.D., Karlberg, T., Rahardja, M.A., Al-Karadaghi, S. & Hansson M.
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53. Tamu Dufe, V., Wei Qui, Muller, I., Hui, R., Walter, R.D. & Al-Karadaghi, S. (2007). Crystal structure of Plasmodium falciparum spermidine synthase in complex with the substrate decarboxylated S-adenosylmethionine and the potent inhibitors 4MCHA and AdoDATO. J. Mol. Biol. 373, 167–177.
54. Elmlund, H., Lundqvist, J., Al-Karadaghi, S., Hansson, M., Hebert, H. &
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55. Sirijovski, N, Lundqvist, J., Rosenbäck, M., Al-Karadaghi, S., Willows, R.D. &
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Biochemistry 47, 4948-4954.
58. Walse, B., Tamu Dufe, V., Svensson, B., Fritzson, I., Dahlberg, L., Khairoullina, A., Wellmar, U. & Al-Karadaghi, S. (2008). The structures of apo- and inhibitor
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60. Fritzson I., Svensson B., Al-Karadaghi S., Walse B., Wellmar U, Nilsson U.J.,
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motor unit of magnesium chelatase. Structure 18, 354-365.
62. Hansson M.D., Karlberg T., Söderberg C.A., Rajan S., Warren M.J., Al-
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63. Williams M, Sprenger J, Human E, Al-Karadaghi S, Persson L, Louw AI,
Birkholtz LM. (2011). Biochemical characterisation and novel classification of monofunctional S-adenosylmethionine decarboxylase of Plasmodium falciparum. Mol Biochem Parasitol. 2011 Jul 22. [Epub ahead of print] 64. Söderberg C.A.G., Shkumatov A.V., Rajan S., Gakh O., Svergun D.I., Isaya G. and Al-Karadaghi S. (2011). Oligomerization propensity and flexibility of yeast
frataxin studied by X-ray crystallography and small angle x-ray scattering Conference proceedings (peer reviewed):
65. Al-Karadaghi, S., Davydova, N., Eliseikina, I., Garber, M., Liljas, A., Nevskaya,
N., Nikonov, S. & Tischenko, S. (2000). Ribosomal components and their structural transitions on and of the ribosome. In: The Ribosome: Structure, Function, Antibiotics, and Cellular Interactions (Eds. Garrett,R.A.; Douthwaite,S.R.; Liljas,A.; Matheson,T; Moore,P.B.; Noller,H.F.), p. 65-72,
66. Liljas, A., Kristensen, O., Laurberg, M., Al-Karadaghi, S., Gudkov, A.,
Martemyanov, K., Hughes, D., Nagaev, I. (2000). The states, conformational dynamics and fusidic acid resistant mutants of EF-G. In: The Ribosome: Structure, Function, Antibiotics, and Cellular Interactions (Eds. Garrett,R.A.; Douthwaite,S.R.; Liljas,A.; Matheson,T; Moore,P.B.; Noller,H.F.), p. 359-365, ASM Press, Washington, D.C. Review articles:
67. Liljas, A., Al-Karadaghi, S. (1997). Structural aspects of protein synthesis.
68. Al-Karadaghi, S., Kristensen, O. & Liljas, A. (2000). A decade of progress in
understanding the structural basis of protein synthesis. Prog. Biophys. Molec. Biol. 73, 167-193.
69. Al-Karadaghi, S., Franco, R., Hansson, M., Shelnutt, J.A., Isaya, G. and Ferreira,
G.C. (2006). Chelatases: distort to select? TIBS 31,135-142.
70. Hunter GA, Al-Karadaghi S, Ferreira GC. (2011). Ferrochelatase: The
convergence of the porphyrin biosynthesis and iron transport pathways. J Porphyr Phthalocyanines 15, 350-356.
71. Franco R, Al-Karadaghi S, Ferreira GC. (2011). Resonance Raman spectroscopic examination of ferrochelatase-induced porphyrin distortion. J Porphyr Phthalocyanines 15, 357-363.
Book review:
72. Al-Karadaghi, S. (2006). Structural Aspects of Protein Synthesis. Acta Crystallogr D Biol Crystallogr. 62, 1101.



ƒ Anamnesis y exploración física. ƒ Exploraciones complementarias. • Actitud ante hemoptisis modera-grave. • Actitud ante hemoptisis masiva o amenazante. • Criterios de ingreso en observación Definición: expulsión de sangre por la boca de origen subglótico con la tos. Clasificación. En función del volumen de sangre emitido: Hemoptisis leve: menor de 30 ml/día, (el esputo hemo

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