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Disease Fact Sheet
What is Cyclospora?
Cyclospora cayetanensis is a parasite composed of one cell, too small to be seen without
a microscope. The first known human cases of illness caused by Cyclospora infection
(i.e., cyclosporiasis) were reported in 1979. Cases began being reported more often in
the mid-1980s. In recent years, outbreaks of cyclosporiasis have been reported in the
United States and Canada.
How is Cyclospora spread?
Cyclospora is spread by people ingesting something, such as water or food, which was
contaminated with infected stool. For example, outbreaks of cyclosporiasis have been
linked to various types of fresh produce. Cyclospora needs time (days or weeks) after
being passed in a bowel movement to become infectious. Therefore, it is unlikely that
Cyclospora is passed directly from one person to another. It is unknown whether
animals can be infected and pass infection to people.
Who is at risk for infection?
People of all ages are at risk for infection. In the past, Cyclospora infection was usually
found in people who lived or traveled in developing countries. However, people can be
infected worldwide, including the United States.
What are the symptoms of infection?
Cyclospora infects the small intestine (bowel) and usually causes watery diarrhea, with
frequent, sometimes explosive, bowel movements. Other symptoms can include loss of
appetite, substantial loss of weight, bloating, increased gas, stomach cramps, nausea,
vomiting, muscle aches, low-grade fever and fatigue. Some people who are infected
with Cyclospora do not have any symptoms.
How soon after infection will symptoms begin?
The time between becoming infected and becoming sick is usually about one week.
How long will symptoms last?
If not treated, the illness may last from a few days to a month or longer. Symptoms
may seem to go away and then return one or more times (relapse).
What should I do if I think I may be infected?
See your health care provider.
How is Cyclospora infection diagnosed?
Your health care provider will ask you to submit stool specimens to see if you are
infected. Because testing for Cyclospora infection can be difficult, you may be asked to
submit several stool specimens over several days. Identification of this parasite in stool
requires special laboratory tests that are not routinely done. Therefore, your health care
provider should specifically request testing for Cyclospora. Your health care provider
may have your stool checked for other organisms that can cause similar symptoms.
How is infection treated?
The recommended treatment for infection with Cyclospora is a combination of two
antibiotics, trimethoprim-sulfamethoxazole, also known as Bactrim*, Septra*, or
Cotrim*. People who have diarrhea should rest and drink plenty of fluids.
ODH-IDCM CYCLOSPORIASIS Page 5/Section 3 Revised 1/2009 I am allergic to sulfa drugs; is there another drug I can take?
No alternative drugs have been identified yet for people who are unable to take sulfa
drugs. See your health care provider for other treatment recommendations.
How is infection prevented?
Avoiding water or food that may be contaminated with stool may help prevent
Cyclospora infection. People who have previously been infected with Cyclospora can
become infected again.
*Use of trade names is for identification only and does not imply endorsement by CDC or ODH.
ODH-IDCM CYCLOSPORIASIS Page 6/Section 3 Revised 1/2009


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