Rc-199

Tetracycline Hydrochloride
Safety Data Sheet
according to Federal Register / Vol. 77, No. 58 / Monday, March 26, 2012 / Rules and Regulations SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
Relevant identified uses of the substance or mixture and uses advised against
: A bacteriostatic antibiotic with activity against both gram-positive and gram-negative bacteria. Details of the supplier of the safety data sheet
G-Biosciences/ Geno Technology, Inc. 9800 Page Avenue St. Louis, MO 63132-1429, USA Tel.1-800-628-7730 Emergency telephone number
: Chemtrec 1-800-424-9300 (USA/Canada), +1-703-527-3887 (Intl)
SECTION 2: Hazards identification
Classification of the substance or mixture
Classification (GHS-US)
Label elements
GHS-US labeling
H319 - Causes serious eye irritation H334 - May cause allergy or asthma symptoms or breathing difficulties if inhaled H335 - May cause respiratory irritation H340 - May cause genetic defects H360 - May damage fertility or the unborn child : P201 - Obtain special instructions before use P202 - Do not handle until all safety precautions have been read and understood P261 - Avoid breathing dust/fume/gas/mist/vapors/spray P264 - Wash . thoroughly after handling P271 - Use only outdoors or in a well-ventilated area P280 - Wear protective gloves/protective clothing/eye protection/face protection P284 - [In case of inadequate ventilation] wear respiratory protection P302+P352 - IF ON SKIN: Wash with plenty of soap and water P304+P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing P305+P351+P338 - If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing P308+P313 - IF exposed or concerned: Get medical advice/attention P312 - Call a POISON CENTER/doctor/…/if you feel unwell P321 - Specific treatment (see . on this label) P332+P313 - If skin irritation occurs: Get medical advice/attention P337+P313 - If eye irritation persists: Get medical advice/attention P342+P311 - If experiencing respiratory symptoms: Call a POISON CENTER/doctor/… P362 - Take off contaminated clothing Tetracycline Hydrochloride
Safety Data Sheet
according to Federal Register / Vol. 77, No. 58 / Monday, March 26, 2012 / Rules and Regulations P403+P233 - Store in a well-ventilated place. Keep container tightly closed P405 - Store locked up P501 - Dispose of contents/container to . Other hazards
Unknown acute toxicity (GHS US)
SECTION 3: Composition/information on ingredients
Substances
Product identifier
Classification (GHS-US)
Eye Irrit. 2A, H319 Resp. Sens. 1B, H334 Muta. 1B, H340 Repr. 1B, H360 STOT SE 3, H335 Mixtures
SECTION 4: First aid measures
Description of first aid measures
: Never give anything by mouth to an unconscious person. IF exposed or concerned: Get medical : Remove to fresh air and keep at rest in a position comfortable for breathing. Call a POISON CENTER/doctor/physician if you feel unwell. : Wash with plenty of soap and water. Wash contaminated clothing before reuse. If skin irritation occurs: Get medical advice/attention. Specific treatment (see . on this label). : Rinse immediately with plenty of water. Obtain medical attention if pain, blinking or redness : Rinse mouth. Do NOT induce vomiting. Obtain emergency medical attention. Most important symptoms and effects, both acute and delayed
: May cause genetic defects. May damage fertility or the unborn child. Indication of any immediate medical attention and special treatment needed
SECTION 5: Firefighting measures
Extinguishing media
: Foam. Dry powder. Carbon dioxide. Water spray. Sand. Special hazards arising from the substance or mixture
Advice for firefighters
: Use water spray or fog for cooling exposed containers. Exercise caution when fighting any chemical fire. Avoid (reject) fire-fighting water to enter environment. : Do not enter fire area without proper protective equipment, including respiratory protection. SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
For non-emergency personnel
For emergency responders
: Equip cleanup crew with proper protection. Environmental precautions
Prevent entry to sewers and public waters. Notify authorities if liquid enters sewers or public waters. Tetracycline Hydrochloride
Safety Data Sheet
according to Federal Register / Vol. 77, No. 58 / Monday, March 26, 2012 / Rules and Regulations Methods and material for containment and cleaning up
: On land, sweep or shovel into suitable containers. Minimize generation of dust. Store away from Reference to other sections
See Heading 8. Exposure controls and personal protection. SECTION 7: Handling and storage
Precautions for safe handling
: Wash hands and other exposed areas with mild soap and water before eat, drink or smoke and when leaving work. Provide good ventilation in process area to prevent formation of vapor. Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Eliminate all ignition sources if safe to do so. Avoid breathing dust/fume/gas/mist/vapors/spray. Use only outdoors or in a well-ventilated area. Conditions for safe storage, including any incompatibilities
: Keep only in the original container in a cool, well ventilated place away from : Keep container Specific end use(s)
SECTION 8: Exposure controls/personal protection
Control parameters
Exposure controls
: When using, do not eat, drink or smoke. SECTION 9: Physical and chemical properties
Information on basic physical and chemical properties
Relative evaporation rate (butyl acetate=1) Tetracycline Hydrochloride
Safety Data Sheet
according to Federal Register / Vol. 77, No. 58 / Monday, March 26, 2012 / Rules and Regulations Other information
SECTION 10: Stability and reactivity
Reactivity
Chemical stability
Possibility of hazardous reactions
Conditions to avoid
Direct sunlight. Extremely high or low temperatures. Incompatible materials
Hazardous decomposition products
SECTION 11: Toxicological information
Information on toxicological effects
Tetracycline Hydrochloride ( \f )64-75-5
: May cause allergy or asthma symptoms or breathing difficulties if inhaled. : May cause genetic defects.May cause genetic defects : May damage fertility or the unborn child.May damage fertility or the unborn child Specific target organ toxicity (single exposure) Specific target organ toxicity (repeated : Not classifiedBased on available data, the classification criteria are not met : Not classifiedBased on available data, the classification criteria are not met Potential Adverse human health effects and : Based on available data, the classification criteria are not met. SECTION 12: Ecological information
Toxicity
Tetracycline Hydrochloride (64-75-5)
Persistence and degradability
Tetracycline Hydrochloride (64-75-5)
Bioaccumulative potential
Tetracycline Hydrochloride (64-75-5)
Mobility in soil
Tetracycline Hydrochloride
Safety Data Sheet
according to Federal Register / Vol. 77, No. 58 / Monday, March 26, 2012 / Rules and Regulations Other adverse effects
SECTION 13: Disposal considerations
Waste treatment methods
: Dispose in a safe manner in accordance with local/national regulations. Dispose of SECTION 14: Transport information
In accordance with ADR / RID / ADNR / IMDG / ICAO / IATA UN number
UN proper shipping name
14.3. Additional information
: No supplementary information available. Overland transport
Transport by sea
Air transport
SECTION 15: Regulatory information
15.1. US Federal regulations
15.2. International regulations
EU-Regulations
Classification according to Regulation (EC) No. 1272/2008 [CLP]
Classification according to Directive 67/548/EEC or 1999/45/EC
National regulations
15.3. US State regulations
Tetracycline Hydrochloride
Safety Data Sheet
according to Federal Register / Vol. 77, No. 58 / Monday, March 26, 2012 / Rules and Regulations SECTION 16: Other information
: REGULATION (EC) No 1272/2008 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL of 16 December 2008 on classification, labeling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006. Full text of H-phrases: see section 16: ------ Serious eye damage/eye irritation Category 2A Specific target organ toxicity (single exposure) Category 3 May cause allergy or asthma symptoms or breathing difficulties if inhaled May damage fertility or the unborn child SDS US GENO (GHS HazCom 2012) This information is based on our current knowledge and is intended to describe the product for the purposes of health, safety and environmental requirements only. It should not therefore be construed as guaranteeing any specific property of the product

Source: http://www.gbiosciences.com/PDF/SDS/RC-199.pdf