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Material Safety Data Sheet
1. PRODUCT AND COMPANY IDENTIFICATION
: Tetracycline hydrochloride
Sigma-Aldrich 3050 Spruce Street SAINT LOUIS MO 63103 USA 2. COMPOSITION/INFORMATION ON INGREDIENTS
Tetracycline hydrochloride
64-75-5 200-593-8
3. HAZARDS IDENTIFICATION
Emergency Overview
OSHA Hazards
Target Organs
HMIS Classification
Health Hazard: 2
Chronic Health Hazard: *
Flammability: 0
Physical hazards: 0

NFPA Rating
Health Hazard: 2
Fire : 0
Reactivity Hazard: 0
Potential Health Effects
Inhalation
May be harmful if inhaled. Causes respiratory tract irritation. May be harmful if absorbed through skin. Causes skin irritation. Sigma-Aldrich Corporation
Fluka - 87130
Ingestion
4. FIRST AID MEASURES
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.Move out of dangerous area.
If inhaled
If breathed in, move person into fresh air. If not breathing give artificial respiration Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
5. FIRE-FIGHTING MEASURES
Flammable properties
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special protective equipment for fire-fighters
Wear self contained breathing apparatus for fire fighting if necessary.
6. ACCIDENTAL RELEASE MEASURES
Personal precautions
Use personal protective equipment. Avoid dust formation. Avoid breathing dust. Ensure adequate ventilation.
Environmental precautions
Do not let product enter drains.
Methods for cleaning up
Pick up and arrange disposal without creating dust. Keep in suitable, closed containers for disposal.
7. HANDLING AND STORAGE
Handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols.
Provide appropriate exhaust ventilation at places where dust is formed. Normal measures for preventive fire
protection.
Storage
Keep container tightly closed in a dry and well-ventilated place.
8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Contains no substances with occupational exposure limit values. Personal protective equipment
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a dust mask type N95 (US) or type P1
(EN 143) respirator. Use respirators and components tested and approved under appropriate government
standards such as NIOSH (US) or CEN (EU).
Sigma-Aldrich Corporation
Fluka - 87130
Hand protection
Handle with gloves.
Eye protection
Safety glasses
Skin and body protection
Choose body protection according to the amount and concentration of the dangerous substance at the work
place.
Hygiene measures
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end
of workday.
9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance
Safety data
10. STABILITY AND REACTIVITY
Storage stability
Stable under recommended storage conditions. May discolor on exposure to light.
Materials to avoid
Strong oxidizing agents
Hazardous decomposition products
Hazardous decomposition products formed under fire conditions.
Carbon oxides, nitrogen oxides (NOx), Hydrogen chloride gas
11. TOXICOLOGICAL INFORMATION
Acute toxicity
Irritation and corrosion
Sensitisation
Prolonged or repeated exposure may cause allergic reactions in certain sensitive individuals. Chronic exposure
Sigma-Aldrich Corporation
Fluka - 87130
This product is or contains a component that is probably not carcinogenic based on its IARC, ACGIH, NTP, or EPA classification. Signs and Symptoms of Exposure
phototoxic reactions, Gastrointestinal disturbance, yellowing of teeth, reduced mineralization Potential Health Effects
Inhalation
May be harmful if inhaled. Causes respiratory tract irritation. May be harmful if absorbed through skin. Causes skin irritation. Ingestion
Target Organs
12. ECOLOGICAL INFORMATION
Elimination information (persistence and degradability)
Ecotoxicity effects
LC50 - Salvelinus namaycush - 220 mg/l - 96 h Further information on ecology
13. DISPOSAL CONSIDERATIONS
Product
Observe all federal, state, and local environmental regulations.Contact a licensed professional waste disposal service
to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator
equipped with an afterburner and scrubber.

Contaminated packaging
Dispose of as unused product.
14. TRANSPORT INFORMATION
DOT (US)
Not dangerous goods
IMDG
Not dangerous goods
IATA
Not dangerous goods
15. REGULATORY INFORMATION
OSHA Hazards
Delayed target organ effects, Irritant
TSCA Status
On TSCA Inventory
DSL Status
All components of this product are on the Canadian DSL list.
SARA 302 Components
SARA 302: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.
Sigma-Aldrich Corporation
Fluka - 87130
SARA 313 Components
SARA 311/312 Hazards
Acute Health Hazard, Chronic Health Hazard
Massachusetts Right To Know Components
No Components Listed
Pennsylvania Right To Know Components
New Jersey Right To Know Components
California Prop. 65 Components
WARNING! This product contains a chemical known in the State of California to cause birth defects or other reproductive harm. 16. OTHER INFORMATION
Further information
Copyright 2007 Sigma-Aldrich Co. License granted to make unlimited paper copies for internal use only., The above
information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our knowledge and is applicable to the product with
regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-
Aldrich Co., shall not be held liable for any damage resulting from handling or from contact with the above product.
See reverse side of invoice or packing slip for additional terms and conditions of sale.
Sigma-Aldrich Corporation
Fluka - 87130

Source: https://www.lakeland.edu/PDFs/MSDS/1292/Tetracycline%20hydrochloride%20(Sigma).pdf