THE VOICE OF NAMI PITTSBURGH SOUTH FEBRUARY 2009 NAMI Pittsburgh South Join us for our next meeting on Wednesday, February 18 at 7:30. We will meetings are held on be watching “Shadow Voices.” A synopsis from the “Shadow Voices” website is the third Wednesday of
as follows: “This program offers an inside look at what it is like to live with a
each month (excluding
mental illness and how individuals and their families find their way through
the month of August)
medical, governmental, societal and spiritual issues. Ten persons from across the
at 7:30 p.m. at
U.S. and many sectors of the population with mental illness tell their stories, plus
Southminster House. Southminster House is
experts and advocates in the field add perspectives and insights. Interviewees
at 801 Washington
include former U.S. First Lady Rosalynn Carter and former U.S. Surgeon General
Road, Mt. Lebanon,
Dr. David Satcher, along with Dr. William Anthony of Boston University, Dr. Joyce
directly across the
Burland, director of educational programs for NAMI, and Thomas Bornemann,
drive from the Mt.
director of the mental health center at the Carter Center.”
Lebanon Public Library. President: Eileen Lovell. Vice President and
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News Editor : Maria Nychis marianychis@ INCLEMENT WEATHER GUIDELINES: In the event of blustery weather please hotmail.com
follow the Mt. Lebanon school district guidelines. If school is cancelled for the Mt.
724.989.3832.
Lebanon schools then the NAMI Pittsburgh South meeting will be cancelled. When
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school is delayed then the meeting will be held. If evening events are cancelled in
Mt. Lebanon then the meeting will be cancelled. Your personal safety is important!
NAMI McKeesport
Do not travel if you local roads are hazardous!
meetings are held on the second Thursday of each month at the Main
Start the New Year off right! Sign up for the Family-to-Family Education Building located on Program! This free education program is a 12-week course for families and Penn State University’s
friends of individuals living with mental illness. Trained family members who have
Campus in McKeesport.
lived with this experience teach the course. Sponsored by NAMI Southwestern
Contact:412. 751.6706 www.McKnami.org.
Pennsylvania, and NAMI Pennsylvania, the Family-to-Family curriculum focuses on
President: Cindy
serious mental illnesses such as schizophrenia, bipolar disorder, major depression,
panic and anxiety disorder, obsessive-compulsive disorder, borderline personality
disorder, and co-occurring mental illness and addictive disorders. Course
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participants will acquire coping and communication techniques, strategies for
handling crisis and relapses, and will receive up-to-date information on medication,
NAMI Southwestern PA phone: 412.366.3788
research, and guidance on locating services and supports. Classes are starting in or 1.888.AMI-SWPA March so register today! Interested parties can contact the NAMI Southwestern NAMI Southwestern PA: www.namiswpa.org info@namiswpa.org NAMI CONNECTION RECOVER SUPPORT GROUPS ARE UP AND RUNNING! NAMI PA on the web:
NAMI Connections is a recovery support group program for adults with mental
www.namipa.nami.org illness of any diagnosis. For those diagnosed with a mental illness, talking with
someone to share coping strategies and insights, as well as problems and
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concerns, can be an important link in the path to recovery. Each support group is
offered through NAMI’s network of local affiliates free of charge. The groups, led
National NAMI Help
by trained individuals who are also in recovery, meet weekly for 90 minutes. To
Line: 1.800.950.NAMI
find out more please cal the NAMI Southwestern PA HelpLine at 1(888) 264-7972
National NAMI on the web: www.nami.org ********* Lack of Grey Matter In Brain Is Linked to Schizophrenia & Bipolar Disorder www.sciencedaily.com
A research study led by scientists from the Gregorio Marañón University Hospital in
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Madrid and the Network of Centres for Biomedical Research in Mental Health
Networks (CIBERSAM) shows that adolescents experiencing a first outbreak of
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psychosis have lower levels of grey matter in their brains than healthy teenagers.
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Strangely, this change was seen in patients suffering from various psychoses,
including bipolar illness and schizophrenia.
The objective of the study was to examine and locate differences in the volume of
grey matter in the brains of healthy people (controls) and individuals diagnosed
with psychotic outbreaks in infancy or adolescence. The researchers broke such
psychosis down into three sub-groups – schizophrenia, bipolar disorder and other
psychoses that did not fit into either of the other two classifications.
The study, published recently in the Journal of the American Academy of Child and
Adolescent Psychiatry, analysed a sample of 121 people aged between 7 and 18,
inclusive. All the patients and controls were examined using magnetic resonance
imaging in order to detect any possible changes in the structure of their brains.
“The interesting thing was that we found common alterations among those with
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two types of clinically-differentiated psychoses, schizophrenia and bipolar disorder,
and this could help to improve diagnosis of these illnesses,” Santiago Reig, one of
the study’s authors and a researcher in the Medical Imaging Laboratory of the
Gregorio Marañón Hospital, tells SINC.
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The study confirmed these lower levels of grey matter, the brain substance in
which neurone cells are concentrated. This lack, which was shared between the
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schizophrenia and type 1 bipolar illness sufferers, means the functions of this part
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of the brain are “somehow atrophied”.
In addition, the technique used by the experts can pinpoint the location of these
alterations. For example, “patients with early psychotic outbreaks (before the age
of 18) showed alterations in the medial prefrontal gyrus region of the brain, which
controls processes such as cognition and the regulation of sensations”, says Reig.
Improving diagnosis NAMI Southwestern PA
“Anything that helps to detect alterations shared between distinct pathologies can
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help in the development of drugs and in finding common characteristics between
these different diseases,” the researcher tells SINC. “Results like these are
fundamental for the diagnosis and treatment of illnesses,” he adds.
However, it is important not to draw any causal link between alterations in this
area of the brain and the appearance of these pathologies. Psychiatric illnesses
need more complex diagnosis. What the research does show, however, is that the
majority of people with schizophrenia and type 1 bipolar illness do suffer from this
lack of grey matter and the majority of healthy people have normal levels of this
“We still do not know whether this loss of grey matter is caused by the illness or
not,” says Reig. This is just one more piece of the puzzle to help in understanding
common features of psychiatric illnesses. “Maybe relating these developments with
other new findings will one day help us to solve the riddle of psychiatric illnesses,”
412.366.3788. Anxious Older Adults May Benefit From Antidepressants www.medicalnewstoday.com
Many older adults worry a lot. Almost one in 10 Americans over age 60 suffer from
an anxiety disorder that causes them to worry excessively about normal things like
health, finances, disability and family. Although antidepressant drugs known as
selective serotonin reuptake inhibitors (SSRIs) can improve anxiety symptoms in
younger adults, little has been known about their effects in older people.
In the largest study of SSRIs in older people with anxiety disorders, a team of
psychiatric researchers found the drug escitalopram (Lexapro®) improved anxiety
YOU ARE NOT ALONE!
symptoms and quality of life. Results are reported in the Jan. 21 issue of the
IF YOU NEED ASSISTANCE DEALING Journal of the American Medical Association.
WITH ANY TYPE OF MENTAL ILLNESS, THE
Patients in the study had Generalized Anxiety Disorder (GAD), a condition of
FOLLOWING
chronic, difficult-to-control worry. Associated symptoms include insomnia, fatigue,
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"A person with Generalized Anxiety Disorder spends, on average, about 40 hours a
ALANON 412.572.5141
week worrying, so it's almost like having a full-time job," says principal investigator
Eric J. Lenze, M.D., associate professor of psychiatry at Washington University
Allegheny County Telephone & Mobile
School of Medicine in St. Louis. "They worry about very real things, but the inability
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to put those worries out of their minds makes the condition disabling."
Older adults with anxiety disorders are typically either not treated or prescribed
Allegheny County Peer
sedative drugs known by trade names such as Valium® and Xanax®. Sedatives
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can relieve anxiety, but their long-term use in older adults is linked to falls and
cognitive impairment. SSRI drugs are thought to be a safer alternative, but it
wasn't clear if they could reduce anxiety in this age group.
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Lenze led the study while at the University of Pittsburgh. His team studied 177
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people over the age of 60. Average age was about 73.
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Half received the SSRI drug escitalopram, and the rest took an inactive placebo.
Participants took one pill per day. If their symptoms didn't improve after four
weeks, a second pill was added. In patients receiving the drug, taking two pills
Allegheny County MH
increased the dosage from 10 mg. to 20 mg. The higher dose more effectively
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After 12 weeks of treatment, 68 percent of patients taking escitalopram had
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improved. About 51 percent of those taking the placebo showed improvement.
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"We found improvements not only in anxiety and level of worry but also in
functioning," Lenze says. "Many people who took the drug felt they were better
Allegheny County
able to carry out daily role activities related to their work or family life."
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Interestingly, the researchers also noted that escitalopram helped some patients
Bipolar and Manic Depressive Support—
"We noticed if their blood pressure was normal, it stayed the same. If they had
high blood pressure, it got better," he says. "It's a preliminary finding, and more
research is needed, but it suggests that anxiety treatment in this age group can
The main side effect of escitalopram in this study was fatigue and sleepiness. That
surprised the research team because the drug is not a sedative; however, the
symptoms usually went away after a few weeks, and the drug was well tolerated
724.775.6304 for more information Borderline Personality
Although escitalopram helped, Lenze calls the benefits modest.
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"That doesn't mean an older adult shouldn't take an SSRI for an anxiety disorder,
but it appears the medication alone usually won't be sufficient," he says. "We're
currently conducting a study that combines drug treatment with a type of
Community Care
psychotherapy called cognitive behavior therapy."
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That study includes investigators at the University of Pittsburgh, the University of
California at San Diego and Washington University. This study treats patients for
Lenze believes the long-term nature of the study will provide better answers about
Depression & Anxiety
how to effectively treat anxiety in older adults and whether doing so improves
Depression and Bipolar Support Alliance
"Most older adults with an anxiety disorder never see a mental health specialist,"
(DBSA) - Meets at
Lenze says. "They are more likely to see a gastroenterologist for GI difficulties or a
rheumatologist for muscle pain than to go to a psychiatrist. They may feel stress
and worry about things, but some other symptom is what gets them to go to the
Lenze, EJ, Rollman BL, Shear MK,Dew MA, Pollock BG, Ciliberti C, Costantino M,
Snyder S, Shi P, Spitznagel E, Andreescu C, Butters MA, Reynolds CF III.
available on the roof (near Peterson Events Center).
Escitalopram for older adults with generalized anxiety disorder: a randomized
controlled trial. Journal of the American Medical Association, vol 301(3), pp. 295-
412.321.6325 for more
This study was supported by the National Institute of Mental Health, the John A.
Hartford Center of Excellence in Geriatric Psychiatry and the University of
Pittsburgh Medical Center endowment in geriatric psychiatry. Forest Laboratories,
www.dbsalliance.org.
which holds the U.S. patent for escitalopram, provided the drug and matching
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Lenze receives research support from Forest Laboratories.
Washington University School of Medicine's 2,100 employed and volunteer faculty
Families of Children
physicians also are the medical staff of Barnes-Jewish and St. Louis Children's
With Challenging
Hospitals. The School of Medicine is one of the leading medical research, teaching,
Behaviors
and patient care institutions in the nation, currently ranked third in the nation by
U.S. News & World Report. Through its affiliations with Barnes-Jewish and St. Louis
Children's Hospitals, the School of Medicine is linked to BJC HealthCare.
HealthChoices Ombudsman Hyperactive Brain May Influence Schizophrenia MEDICAL ASSISTANCE www.psychcentral.com TRANSPORTATION PROGRAM (MATP) at
New imaging studies suggest an overactive brain system may blur internal and
external realities among individuals with schizophrenia.
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The traditional view of schizophrenia is that the disturbed thoughts, perceptions
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and emotions that characterize the disease are caused by disconnections among
the brain regions that control these different functions.
But this study, appearing in the advance online issue of the Proceedings of the National Academy of Sciences, found that schizophrenia also involves an excess of
connectivity between the so-called default brain regions, which are involved in self-
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reflection and become active when we are thinking about nothing in particular, or
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“People normally suppress this default system when they perform challenging
tasks, but we found that patients with schizophrenia don’t do this,” said John D.
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Gabrieli, a professor in the McGovern Institute for Brain Research at MIT and one
Depressive/Bipolar Support – Meets at St
Paul's Episcopal Church (Washington Road and
“We think this could help to explain the cognitive and psychological symptoms of
schizophrenia.” Gabrieli added that he hopes the research might lead to ways of
predicting or monitoring individual patients’ response to treatments for this mental
illness, which occurs in about 1 percent of the population.
Tony at 412.779.5834 Obsessive Compulsive
Schizophrenia has a strong genetic component, and first-degree relatives of
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patients (who share half their genes) are 10 times more likely to develop the
disease than the general population. The identities of these genes and how they
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The researchers thus studied three carefully matched groups of 13 subjects each:
schizophrenia patients, nonpsychotic first-degree relatives of patients and healthy
controls. They selected patients who were recently diagnosed, so that differences
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in prior treatment or psychotic episodes would not bias the results.
Program is a twelve- month rental subsidy
The subjects were scanned by functional magnetic resonance imaging (fMRI) while
resting and while performing easy or hard memory tasks. The behavioral and
clinical testing were performed by Larry J. Seidman and colleagues at Harvard
Medical School, and the imaging data were analyzed by first author Susan
Whitfield-Gabrieli, a research scientist at the MIT Martinos Imaging Center at the
The researchers were especially interested
recovering, single men and women, single men
in the default system, a network of brain regions whose activity is suppressed
when people perform demanding mental tasks. This network includes the medial
prefrontal cortex and the posterior cingulate cortex, regions that are associated
with self-reflection and autobiographical memories and which become connected
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into a synchronously active network when the mind is allowed to wander.
nks.org/pennFree/ for more information!
Whitfield-Gabrieli found that in the schizophrenia patients, the default system was
both hyperactive and hyperconnected during rest, and it remained so as they
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performed the memory tasks. In other words, the patients were less able than
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healthy control subjects to suppress the activity of this network during the task.
Interestingly, the less the suppression and the greater the connectivity, the worse
they performed on the hard memory task, and the more severe their clinical
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“We think this may reflect an inability of people with schizophrenia to direct mental
resources away from internal thoughts and feelings and toward the external world
www.recovery-inc.org
in order to perform difficult tasks,” Whitfield-Gabrieli explained.
The hyperactive default system could also help to explain hallucinations and
Refer the Uninsured
paranoia by making neutral external stimuli seem inappropriately self-relevant. For
Project:
instance, if brain regions whose activity normally signifies self-focus are active
while listening to a voice on television, the person may perceive that the voice is
their Helpline at (800) 274-3258 or TTY line
The default system is also overactive, though to a lesser extent, in first-degree
relatives of schizophrenia patients who did not themselves have the disease. This
suggests that overactivation of the default system may be linked to the genetic
cause of the disease rather than its consequences.
The default system is a hot topic in brain imaging, according to John Gabrieli,
partly because it is easy to measure and because it is affected in different ways by
Research Into the Causes of Schizophrenia
Research Brain Tissue Donation Info. SQUIRREL HILL HEALTH CENTER-For Real and Perceived Stigma in Schizophrenia Severe, Widespread www.medscape.com
of the poverty level. Hours are M-TH 9am-
A global study shows that individuals with schizophrenia both experience and
A cross-sectional survey of individuals with schizophrenia from 27 countries by
investigators from King's College London, in the United Kingdom, revealed that
43% to 47% of individuals with schizophrenia experienced discrimination in making
or keeping friends or maintaining relationships with family members, while 29%
experienced discrimination in finding or keeping a job and 27% experienced
discrimination in their intimate or sexual relationships.
Rebecca LaBovick,
"Discrimination has not been systematically measured before in this group, and we
found it was common and severe," principal investigator Graham Thornicroft, PhD,
from King's College London, told Medscape Psychiatry.
(412) 621.6513 x 101
The study also revealed 2 surprising findings, he noted. First, discrimination is
uniform among diverse countries. Second, about 1 in 3 individuals anticipate
discrimination in close relationships or job seeking that does not materialize.
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"Clinicians need to take these issues very seriously and never offer life-denying
statements such as 'you will never work again,' " said Dr. Thornicroft
The study is published online January 21 in the Lancet.Well Spouse Support The Ultimate Stigma
Many patients with mental illness experience stigma caused by other people's lack
of knowledge, prejudicial attitudes, and discriminatory behavior. This can lead to
impoverishment, social marginalization, and low quality of life.
"By comparison with other disorders, mental illnesses are typically more
stigmatized, and this has been called the ultimate stigma," the authors write.
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Most of the previous research on stigma and mental illness has mainly focused on
hypothetical situations. Such investigations, say the authors, emphasize what
healthy people might say rather than focusing on the experiences of individuals
To measure both experienced and anticipated discrimination — defined as unjust
distinction in the treatment of different categories of people — the researchers
conducted a cross-sectional survey using face-to-face interviews among 732 people
diagnosed with schizophrenia, 1 of the most stigmatizing mental disorders.
Participants were drawn from centers that were part of the International Study of
Discrimination and Stigma Outcomes (INDIGO) network in 27 countries throughout
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The subjects had a mean age of 39 years, and 62% were men.
To address the need for an internationally reliable measure of discrimination, the
researchers developed the discrimination and stigma scale (DISC), which was
translated and cross-culturally adapted for all study sites.
The scale contains 32 items to determine experienced discrimination and 4 items to
To determine discrimination, the participants were asked whether they had been
treated differently and about a range of work, social, and everyday life situations.
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If they reported discrimination, they were asked to provide a verbatim example.
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The investigators found negative discrimination was a very common experience in
this patient group. In addition, longer duration of illness and receiving compulsory
treatment were both associated with higher levels of negative discrimination.
Positive discrimination was less common, although 24% of study participants
reported positive discrimination in treatment by family, and between 11% and
18% reported positive discrimination for obtaining welfare, housing, and medical
comfortable environment where people can go to
Of the 69% of participants who reported anticipating discrimination in finding or
keeping work, only 33% had actually experienced this type of discrimination.
Similarly, of the 60% of participants who reported anticipating discrimination in
intimate relationships, only 26% actually experienced discrimination of this type.
This finding, say the authors, indicates the importance of including methods that
increase self-esteem in stigma-reduction strategies for individuals with mental
illness and has important implications for education of employers about mental
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For example, disability discrimination legislation might require additional
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interventions to reduce anticipated discrimination, so individuals with mental
illnesses apply for and obtain jobs, they suggest.
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"As a next step, antidiscrimination legislation needs to be applied to people with
mental as well as physical disabilities," said Dr. Thornicroft.
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According to the investigators, this study opens the door to a" new arena of
research characterizing the nature and extent of discrimination against people with
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PA 15213, 412.683.7140. Second Hope –
"This landmark study encourages us not only to continue fighting stigma in a global
coalition, but also to step up our efforts," writes Beate Schulze, MD, from the
University of Zurich, in Switzerland, in an accompanying editorial.
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There are several key messages that can be derived from this research, says Dr.
Schulze, among them, the need for clinical interventions to enhance patients' self-
esteem. Further, she writes, there is a need to improve the quality of psychiatric
treatment and more closely scrutinize clinicians' attitudes about mental illness and
refute "fatalistic notions" about prognosis and treatment.
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By bringing together structural and cognitive perspectives that have not previously
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been combined, the INDIGO study is "breaking new ground" and pointing in new
AFFECTED BY MENTAL ILLNESS. CALL TO TALK TO SOMEONE WHO WILL LISTEN, UNDERSTAND AND Mark your calendar for April 18, 2009 NAMI SWPA’s 8th Annual Conference TAKE BACK YOUR LIFE Living Longer with Serious Mental Illness NAMI Pittsburgh South Membership Form 2009 ___ Enclosed is my check for $35 for family membership in NAMI Pittsburgh South,
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