Praveen rao p

Research Publications

Review articles

Tarek Mohamed, Praveen P N Rao Alzheimer’s disease: Emerging trends in small molecule therapies.
Curr. Med. Chem. 18, 4299-4320, (2011).
Tarek Mohamed, Praveen P N Rao Current and emerging at-site pain medications: A review. Journal
of Pain Research (2011) In Press
Praveen P N Rao, Saad, N. Kabir, Tarek Mohamed. Nonsteroidal anti-inflammatory drugs (NSAIDs):
Progress in small molecule drug development. Pharmaceuticals 3, 1530-1549, (2010).
P. N. Praveen Rao, Rajesh K. Grover. Apricoxib, a COX-2 inhibitor for the potential treatment of pain
and cancer. IDrugs 12, 711-722, (2009).
P. N. Praveen, Rao, Edward, E. Knaus. Evolution of nonsteroidal anti-inflammatory drugs (NSAIDs):
COX inhibition and beyond. J. Pharm. Pharm. Sci. 11, 81s-110s, (2008).

Research articles

Tarek Mohamed, Jacky C K Yeung, Praveen P N Rao Development of 2-substituted-N-(naphth-1-
ylmethyl) and N-benzhydrylpyrimidin-4-amines as dual cholinesterase and A-aggregation inhibitors:
synthesis and biological evaluation. Bioorg. Med. Chem. Lett. (2011). In press
Tarek Mohamed.; Xiaobei Zhao.; Lila K. Habib.; Jerry Yang.; Praveen P. N. Rao. Design, synthesis
and structure-activity relationship (SAR) studies of 2,4-disubstituted pyrimidine derivatives: dual
activity as cholinesterase and abeta-aggregation inhibitors. Bioorg. Med. Chem. 19, 2269-2281 (2011).
Rahim, M. R., Praveen P. N. Rao., Bhardwaj, A., Kaur, J., Huang, Z., Knaus, E. E. Isomeric acetoxy
analogs of celecoxib and their evaluation as cyclooxygenase inhibitors. Bioorg. Med. Chem. Lett.
(2011). In Press
Tarek Mohamed, Praveen P N Rao. Design, synthesis and evaluation of 2,4-disubstituted pyrimidines
as cholinesterase inhibitors. Bioorg. Med. Chem. Lett. 20, 3606-3609, (2010).
Rao, P. N. P.;
Synthesis and biological evaluation of N-difluoromethyl-1,2-dihydropyrid-
2-one acetic acid regioisomers: dual inhibitors of cyclooxygenases and 5-lipoxygenase. Bioorg. Med.
Chem. Lett. 20, 2168-2173 (2010).
Yu, G.; Chowdhury, M. A.; Khaled R. A. Abdellatif, Ying Dong, P. N. Praveen Rao, Dipankar Das,
Carlos A. Velázquez, Mavanur R. Suresh, Edward E. Knaus. Phenylacetic acid regioisomers possessing
a N-difluoromethyl-1,2-dihydropyrid-2-one pharmacophore: Evaluation as dual inhibitors of
cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity. Bioorg. Med. Chem. Lett. 20,
896-902 (2010).
O2-
acetoxymethyl-protected diazeniumdiolate-based NSAIDs (NONO-NSAIDs): synthesis, nitric oxide
release, and biological evaluation studies. Bioorg. Med. Chem. 15, 4767-4774 (2007).
Zarghi, A.; P. N. Praveen, Rao.; Edward, E. Knaus. Synthesis and biological evaluation of
methanesulfonamide analogues of rofecoxib: Replacement of methanesulfonyl by methanesulfonamido
decreases cyclooxygenase-2 selectivity. Bioorg. Med. Chem. 15, 1056-1061 (2007).
Zarghi, A.; P. N. Praveen, Rao.; Edward, E. Knaus. Design and synthesis of new rofecoxib analogs as
selective cyclooxygenase-2 (COX-2) inhibitors: Replacement of the methanesulfonyl pharmacophore
by a N-acetylsulfonamido bioisostere. J. Pharm. Pharm. Sci. 10, 159-167 (2007).
Qiao-Hong, Chen.; P. N. Praveen, Rao.; Edward, E. Knaus. Synthesis and biological evaluation of a
novel class of rofecoxib analogues as dual inhibitors of cyclooxygenases (COXs) and lipoxygenases
(LOXs). Bioorg. Med. Chem. 14, 7898-7909 (2006).
Moreau, A.; Qiao-Hong, Chen.; P. N. Praveen, Rao.; Edward, E. Knaus. Design, synthesis, and
biological evaluation of (E)-3-(4-methanesulfonylphenyl)-2-(aryl)acrylic acids as dual inhibitors of
cyclooxygenases and lipoxygenases. Bioorg. Med. Chem. 14, 7716-7727 (2006).
Zarghi, A.; . N. Praveen, Rao.; Edward, E. Knaus.
Synthesis and biological evaluation of 1,3-diphenylprop-2-en-1-ones possessing a methanesulfonamido
or an azido pharmacophore as cyclooxygenase-1/-2 inhibitors. Bioorg. Med. Chem. 14, 7044-7050
(2006).
Moreau, A.; P. N. Praveen, Rao.; Edward, E. Knaus. Synthesis and biological evaluation of acyclic
triaryl (Z)-olefins possessing a 3,5-di-tert-butyl-4-hydroxyphenyl pharmacophore: Dual inhibitors of
cyclooxygenases and lipoxygenases. Bioorg. Med. Chem. 14, 5340-5350 (2006).
Anana, R.; P. N. Praveen, Rao.; Qiao-Hong, Chen.; Edward, E. Knaus. Synthesis and biological
evaluation of linear phenylethynylbenzenesulfonamide regioisomers as cyclooxygenase-1/-2 (COX-1/-
2) inhibitors. Bioorg. Med. Chem. 14, 5259-5265 (2006).
P. N. Praveen, Rao.; Qiao-Hong, Chen.; Edward, E. Knaus. Synthesis and structure-activity
relationship studies of 1,3-diphenylprop-2-yn-1-ones: Dual inhibitors of cyclooxygenases and
lipoxygenases. J. Med. Chem. 49, 1668-1683 (2006).
Zarghi, A.; Arfaee, S.; P. N. Praveen, Rao.; Edward, E. Knaus. Design, synthesis, and biological
evaluation of 1,3-diarylprop-2-en-1-ones: A novel class of cyclooxygenase-2 inhibitors. Bioorg. Med.
Chem. 14, 2600-2605 (2006).
P. N. Praveen, Rao.; Qiao-Hong, Chen.; Edward, E. Knaus. Synthesis and biological evaluation of 1,3-
diphenylprop-2-yn-1-ones as dual inhibitors of cyclooxygenases (COXs) and lipoxygenases (LOXs).
Bioorg. Med. Chem. Lett. 15, 4842-4845 (2005).
Qiao-Hong, Chen.; P. N. Praveen, Rao.; Edward, E. Knaus. Design, synthesis and biological
evaluation of linear 1-(4-, 3- or 2-methylsulfonylphenyl)-2-phenylacetylenes: A novel class of
cyclooxygenase-2 (COX-2) inhibitors. Bioorg. Med Chem. 13, 6425 -6434 (2005).
Qiao-Hong, Chen.; P. N. Praveen, Rao.; Edward, E. Knaus. Design, synthesis, and biological
evaluation of N-acetyl-2-(or 3-)carboxymethylbenzenesulfonamides as cyclooxygenase isozyme
inhibitors. Bioorg. Med. Chem. 13, 4694-4703 (2005).
Velázquez, C. A.; P. N. Praveen, Rao.; Edward, E. Knaus. Novel nonsteroidal antiinflammatory drugs
possessing a nitric oxide donor diazen-1-ium-1,2-diolate moiety: Design, synthesis, biological
evaluation, and nitric oxide release studies. J. Med. Chem. 48, 4061-4067 (2005).
Velázquez, C. A.; P. N. Praveen, Rao.; McDonald, R.; Edward E. Knaus. Synthesis and biological
evaluation of 3,4-diphenyl-1,2,5-oxadiazole-2-oxides and 3,4-diphenyl-1,2,5-oxadiazoles as potential
hybrid COX-2 inhibitor/nitric oxide donor agents. Bioorg. Med. Chem. 13, 2749-2757 (2005).
Qiao-Hong, Chen.; P. N. Praveen, Rao.; Edward, E. Knaus. Design, synthesis, and biological
evaluation of N-acetyl-2-carboxybenzenesulfonamides: A novel class of cyclooxygenase-2 (COX-2)
inhibitors. Bioorg. Med. Chem. 13, 2459-2468 (2005).
Md. Jashim, Uddin.; P. N. Praveen, Rao.; McDonald, R.; Edward, E. Knaus. Design and synthesis of
(E)-1,1,2-triarylethenes: Novel inhibitors of the cyclooxygenase-2 (COX-2) isozyme. Bioorg. Med.
Chem. Lett. 15, 439-442 (2005).
Md. Jashim, Uddin.; P. N. Praveen, Rao, Edward, E. Knaus. Design and synthesis of (Z)-1,2-diphenyl-
1-(4-methanesulfonamidophenyl)alk-1-enes and (Z)-1-(4-azidophenyl)-1,2-diphenylalk-1-enes: Novel
inhibitors of cyclooxygenase-2 (COX-2) with antiinflammatory and analgesic activity. Bioorg. Med.
Chem. 13, 417-424 (2005).
P. N. Praveen, Rao.; Md. Jashim, Uddin.; Edward, E. Knaus. Design, synthesis and structure-activity
relationship (SAR) studies of substituted-3,4,6-triphenylpyran-2-ones as selective cyclooxygenase-2
inhibitors J. Med. Chem. 47, 3972-3990 (2004).
Md. Jashim, Uddin.; P. N. Praveen, Rao.; McDonald, R.; Edward, E. Knaus. A new class of acyclic 2-
alkyl-1,1,2-triaryl (Z)-olefins as selective cyclooxygenase-2 (COX-2) inhibitors. J. Med. Chem. 47,
6108-6111 (2004).
Md. Jashim, Uddin.; P. N. Praveen, Rao.; Edward E. Knaus. Design and synthesis of acyclic triaryl
(Z)-olefins: a novel class of cyclooxygenase-2 (COX-2) inhibitors. Bioorg. Med. Chem. 12, 5929-5940
(2004).
Md. Jashim, Uddin.; P. N. Praveen, Rao, Md. Abdur, Rahim.; McDonald, R.; Edward, E. Knaus. A
new class of acyclic 2-alkyl-1,2-diaryl (E)-olefins as selective cyclooxygenase-2 (COX-2) inhibitors.
Bioorg. Med. Chem. Lett. 14, 4911-4914 (2004).
Md. Jashim, Uddin.; P. N. Praveen, Rao,.;Edward E. Knaus. Methylsulfonyl and hydroxyl substituents
induce (Z)-stereocontrol in the McMurry olefination reaction. Synlett 1513-1516 (2004).
Md. Jashim, Uddin.; P. N. Praveen, Rao.; Edward, E. Knaus. Design of acyclic triaryl olefins: a new
class of potent and selective cyclooxygenase-2 (COX-2) inhibitors. Bioorg. Med. Chem. Lett. 14, 1953-
1956 (2004).
Zarghi, A.; P. N. Praveen, Rao.; Edward, E. Knaus. Sulfonamido, azidosulfonyl and N-
acetylsulfonamido
methanesulfonylphenyl)-2(5H)furanone is a potent and selective cyclooxygenase-2 inhibitor. Bioorg.
Med. Chem. Lett. 14, 1957-1960 (2004).
P. N. Praveen, Rao.; Mohsen, Amini.; Huiying, Li.; Amgad, G. Habeeb.; Edward, E. Knaus. Design,
synthesis and biological evaluation of 6-substituted-3-(4-methanesulfonylphenyl)-4-phenylpyran-2-
ones: a novel class of diarylheterocyclic selective cyclooxygenase-2 inhibitors. J. Med. Chem. 46,
4872-4882 (2003).
P. N. Praveen, Rao.; Mohsen, Amini.; Huiying, Li.; Amgad, G. Habeeb.; Edward, E. Knaus. 6-alkyl,
alkoxy or alkylthio-substituted 3-(4-methanesulfonylphenyl)-4-phenylpyran-2-ones: a novel class of
diarylheterocyclic selective cyclooxygenase-2 inhibitors. Bioorg. Med. Chem. Lett. 13, 2205-2209
(2003).
Md. Jashim, Uddin.; P. N. Praveen, Rao.; Edward, E. Knaus. Design and synthesis of novel rofecoxib
analogs as potential selective cyclooxygenase-2 (COX-2) inhibitors: replacement of the methylsulfonyl
pharmacophore by a sulfonylazide bioisostere. J. Heterocyl. Chem. 40, 861-868 (2003).
Srinath, P.; P. N. Praveen, Rao.; Edward, E. Knaus.; Suresh, M. R. Effect of cyclooxygenase-2 (COX-
2) inhibitors on prostate cancer cell proliferation. Anticancer Res. 23, 3923-3928 (2003).
Md. Jashim, Uddin.; P. N. Praveen, Rao.; Edward, E. Knaus. Design and synthesis of novel celecoxib
analogs as selective cyclooxygenase-2 (COX-2) inhibitors: replacement of the sulfonamide
pharmacophore by a sulfonylazide bioisostere. Bioorg. Med. Chem. 11, 5273-5280 (2003).
Md. Abdur, Rahim.; P. N. Praveen, Rao.; Edward, E. Knaus. Synthesis of 4-alkyl-1,2-diphenyl-3,5-
dioxopyrazolidines possessing aryl methylsulfonyl and sulfonamide pharmacophores for evaluation as
selective cyclooxygenase-2 (COX-2) inhibitors. J. Heterocyl. Chem. 39, 1309-1314 (2002).
Huiying, Li.; P. N. Praveen, Rao.; Amgad, G. Habeeb.; Edward, E. Knaus. Design, syntheses and
evaluation of 2,3-diphenylcycloprop-2-en-1-ones and oxime derivatives as potential cyclooxygenase-2
(COX-2) inhibitors with analgesic-antiinflammatory activity. Drug Develop. Res. 57, 6-17 (2002).
Md. Abdur Rahim, P. N. Praveen Rao, Edward E. Knaus. Isomeric acetoxy analogs of rofecoxib: a
novel class of highly potent and selective cyclooxygenase-2 inhibitors. Bioorg. Med. Chem. Lett. 12,
2753-2756 (2002).
P. N. Praveen, Rao.; Amgad, G. Habeeb.; Edward, E. Knaus. Design and syntheses of Novel 1,1-
dihalo-2,3-diphenylcyclopropanes as potential cyclooxygenase-2 (COX-2) inhibitors with analgesic-
antiinflammatory activity. Drug Develop. Res. 55, 79-90 (2002).
Amgad, G. Habeeb.; P. N. Praveen, Rao.; Edward, E. Knaus. Design and synthesis of 4,5-
diphenylisoxazolines: novel inhibitors of cyclooxygenase-2 (COX-2) with analgesic and
antiinflammatory activity. J. Med. Chem. 44, 2921-2927 (2001).
Amgad, G. Habeeb.; P. N. Praveen, Rao.; Edward, E. Knaus. Design and synthesis of celecoxib and
rofecoxib analogues as cyclooxygenase-2 (COX-2) inhibitors: replacement of sulfonamide and
methylsulfonyl pharmacophores by an azido bioisostere. J. Med. Chem. 44, 3039-3042 (2001).
Amgad, G. Habeeb.; P. N. Praveen, Rao.; Edward E. Knaus. Design and syntheses of diarylisoxazoles:
novel inhibitors of cyclooxygenase-2 (COX-2) with analgesic-antiinflammatory activity. Drug Develop.
Res. 51; 273-286 (2000).
Sammy, Agudoawu.; Huiying, Li.; Amgad, G. Habeeb.; P. N. Praveen, Rao.; Mavanur, R. Suresh.;
Edward, E. Knaus. Design and syntheses of methyl 2-methyl-2-[2-(4-benzoyl-5-phenyl-7-halo-2-
azabicyclo[4.1.0]hept-3-ene)acetates: novel inhibitors of cyclooxygenase-2 (COX-2) with analgesic-
antiinflammatory activity. Drug Develop. Res. 49, 75-84 (2000).
Mahadev, Rao.; P. N. Praveen, Rao.; Ravindra, Kamath.; M. N. A. Rao. Reduction of cisplatin
induced nephrotoxicity by cystone, polyherbal ayurvedic preparation in C57BL/6J mice bearing B16F1
melanoma without reducing its antitumor activity. J. Ethnopharmacol. 68, 77-81 (1999).
P. N. Praveen, Rao.; Mahadev, Rao.; M. N. A. Rao .Gastroprotective effect of 1-phenyl-3 (4-hydroxy-
3,5-di-tert.butylphenyl)-prop-en-1-one in rats. J. Pharm. Pharmacol. 50, 1371-1375 (1998).

Abstracts/Papers/Posters/Lectures presented:

1) Praveen P N Rao, Mohamed T, Yeung C. K, Zhao X, Habib L, Yang J. Development of 2,4-disubstituted
pyrimidine ring templates: dual cholinesterase and amyloid-β inhibitors. The 94th Canadian Chemistry Conference and Exhibition (CSC 2011), Montreal, Canada 2011. 2) Tarek Mohamed, Yeung,C. K, Zhao X, Habib L, Yang Y, Praveen P N Rao. Design, synthesis and
structure-activity relationship (SAR) studies of 2,4-disubstituted pyrimidine derivatives: Multi-functional small molecules for the potential treatment of Alzheimer’s disease. Association of Faculties of Pharmacy of Canada (AFPC 2011), Winnipeg, Canada 2011. 3) Tarek Mohamed, P N P Rao. The design, synthesis and structure-activity relationship (SAR) studies of 2,4-
disubstituted-pyrimidine derivatives as cholinesterase (ChE) inhibitors. The 93rd Canadian Chemistry Conference and Exhibition (CSC 2010), Toronto, Canada 2010. 4) Özadali, K.; Özkanli, F.; Jain, S.; Rao, P. N. P.; Velázquez, C. Synthesis and cyclooxygenase inhibitory
activities of some 1,3,4-thiadiazole and 1,2,4-triazole-5-thione derivatives of isoxazolo[4,5-d]pyridazin-4(5H)-ones (poster) 4th International Meeting on Medicinal and Pharmaceutical Chemistry, Ankara, Turkey 2010. 5) Kwon, H.J., Zhao, B., Rao, P.N.P. Application of digital volume correlation algorithm to cell mechanics,”
Proceedings of the ASME International Mechanical Engineering Conference & Exposition (IMECE 2009), Lake Buena Vista, U. S. A. 6) Carlos A. Velazquez, Edward E. Knaus, P.N. Praveen Rao, Quiao-Hong Chen, Thomas Wilde, Larry
Keefer. Novel NONO-NSAIDs possessing a nitric oxide donor diazeniumdiolate moiety. 4th International Conference: Biology, Chemistry and Therapeutic Applications of Nitric Oxide, presented by the Nitric Oxide Society (2006), Monterey, U. S. A. 7) Edward E. Knaus, Anne Moreau, P. N. Praveen Rao. Acyclic triaryl (Z)-olefins: Dual inhibitors of
cyclooxygenases and lipoxygenases. 89th Conference of the Canadian Society for Chemistry 2006 (CSC), Halifax, Canada. 8) P. N. Praveen Rao, Qiao-Hong Chen, Edward E. Knaus. Synthesis and biological evaluation of 1,3-
diphenylprop-2-yn-1-ones as dual inhibitors of cyclooxygenases (COXs) and lipoxygenases (LOXS). Pharmacy Research Day, Faculty of Pharmacy & Pharmaceutical Sciences, 2005, University of Alberta, Edmonton, Canada. 9) P. N. Praveen Rao, `Design, synthesis and evaluation of novel anti-inflammatory agents’ invited guest
lecture, Department of Chemistry, The Scripps Research Institute, 2004, CA, U. S. A. 10) Anne Moreau, P. N. Praveen Rao, Edward E. Knaus. Design, synthesis and biological evaluation of a new
class of acyclic triaryl (Z)-olefins as selective cyclooxygenase-2 (COX-2) and/or 5-lipoxygenase (5-LOX) inhibitors: Incorporating the 2,6-di-tert-butylphenol pharmacophore. Pharmacy Research Day, Faculty of Pharmacy & Pharmaceutical Sciences, 2005, University of Alberta, Edmonton, Canada. 11) Qiao-Hong Chen, P. N. Praveen Rao, Edward E. Knaus. Design, synthesis and biological evaluation of
linear 1-(4-, 3- or 2-methylsulfonylphenyl)-2-phenylacetylenes: A novel class of cyclooxygenase-2 (COX-2) inhibitors. Pharmacy Research Day, Faculty of Pharmacy & Pharmaceutical Sciences, 2005, University of Alberta, Edmonton, Canada. 12) Abdullah Mahmud, P. N. Praveen Rao, Afsaneh Lavasanifar. Synthesis of the poly (ethylene oxide)-
block-poly-(ε-caprolactone) (PEO-b-PCL) block copolymer having functional groups on the PCL block. Pharmacy Research Day, Faculty of Pharmacy & Pharmaceutical Sciences, 2005, University of Alberta, Edmonton, Canada. 13) Edward E. Knaus, Qiao-Hong Chen, P. N. Praveen Rao, Design, synthesis, and biological evaluation of N-
acetyl-2-carboxybenzenesulfonamides: a novel class of cyclooxygenase-2 (COX-2) inhibitors. 88th Conference of the Canadian Society for Chemistry 2005 (CSC), Saskatoon, Canada. 14) P. N. Praveen Rao, Md. Jashim Uddin, Edward E. Knaus. A new class of acyclic 2-alkyl-1,1,2-triaryl (Z)-
olefins as selective cyclooxygenase-2 (COX-2) inhibitors. Pharmacy Research Day, Faculty of Pharmacy & Pharmaceutical Sciences, 2004, University of Alberta, Edmonton, Canada 15) P. N. Praveen Rao, `Parkinson’s disease’ invited guest lecture, 2004, St. Joseph's Auxiliary Hospital
Edmonton, Alberta, Canada. 16) E. E. Knaus, M. J. Uddin, P. N. Praveen Rao. Design of acyclic triaryl olefins: a new class of highly
potent and selective COX-2 inhibitors. Canadian Society for Pharmaceutical Sciences (CSPS), 7th annual symposium 2004, Vancouver, British Columbia, Canada. 17) P. N. Praveen Rao, `Parkinson’s disease and cyclooxygenase-2 (COX-2)’ invited guest lecture, 2003, The
Parkinson’s Society of Alberta, Edmonton General, Edmonton, Alberta, Canada. 18) P. N. Praveen Rao, `Drug design concepts: application to selective cyclooxygenase-2 inhibitors’ podium
presentation, Leonard Wiebe Pharmacy Research Day, Faculty of Pharmacy & Pharmaceutical Sciences, 2003, University of Alberta, Edmonton, Canada (Award for best graduate student podium presentation). 19) P. N. Praveen Rao, Edward E. Knaus. Design, synthesis and evaluation of a novel class of substituted-
3,4,6-triphenylpyran-2-ones as selective cyclooxygenase-2 (COX-2) inhibitors. Leonard Wiebe Pharmacy Research Day, Faculty of Pharmacy & Pharmaceutical Sciences, 2003, University of Alberta, Edmonton, Canada (Wyeth graduate student poster award). 20) P. N. Praveen Rao, Edward E. Knaus. Design, synthesis and evaluation of a novel class of substituted-
3,4,6-triphenylpyran-2-ones as selective cyclooxygenase-2 (COX-2) inhibitors. 39th IUPAC Congress & 86th Conference of the Canadian Society for Chemistry 2003 (CSC), Ottawa, Canada. 21) M. J. Uddin, P. N. P. Rao, Edward E. Knaus. Design of acyclic triaryl olefins: a new class of highly potent
and selective COX-2 inhibitors. IUPAC International Symposium on Organo-Metallic Chemistry 2003 (OMCOS-12), Toronto, Canada. 22) P. N. P. Rao, M. Amini, Edward E. Knaus. Novel 6-alkylthio-3-(4-methanesulfonylphenyl)-4-
phenylpyran-2-ones as selective cyclooxygenase-2 (COX-2) inhibitors with analgesic-antiinflammatory activities. IUPAC International Symposium on Bioorganic Chemistry 2002 (ISBOC-6), Toronto, Canada. 23) M.J. Uddin, P. N. Praveen Rao, E.E. Knaus. Design, synthesis and biological evaluation of celecoxib and
rofecoxib analogs as selective COX-2 inhibitors: Replacement of sulfonamide and sulfonylmethyl pharmacophores by a sulfonylazide bioisostere. Canadian Society for Pharmaceutical Sciences (CSPS), 5th annual symposium 2002, Banff, Alberta, Canada. 24) M.A. Rahim, P. N. Praveen Rao, E.E. Knaus. Design, synthesis and biological evaluation of rofecoxib
analogs as acetylating selective COX-2 inhibitors. Canadian Society for Pharmaceutical Sciences (CSPS), 5th annual symposium 2002, Banff, Alberta, Canada. 25) P. N. Praveen Rao, `Parkinson’s disease: a perspective’ invited guest lecture, 2002, The Parkinson’s
Society of Alberta, Edmonton General, Edmonton, Alberta, Canada. 26) Edward E. Knaus, Amgad G. Habeeb, P.N. Praveen Rao. Design and syntheses of diarylisoxazoles: novel
inhibitors of cyclooxygenase-2 (COX-2) with analgesic-antiinflammatory activity. 84th Canadian Society for Chemistry Conference 2001 (CSC), Montreal, Quebec, Canada. 27) P. N. Praveen Rao, Edward E. Knaus. Novel 6-alkylthio-3-(4-methanesulfonylphenyl)-4-phenylpyran-2-
ones as selective cyclooxygenase-2 (COX-2) inhibitors. Research revelations 2001, University of Alberta, Edmonton, Canada. 28) E. E. Knaus, Agudoawu S, Li. H, Habeeb A.G, P. N. P. Rao, Design and syntheses of 2-methyl-2-methyl-
2-[2-(4-benzoyl-5-phenyl-7-halo-2-azabicyclo[4.1.0]hept-3-ene] cyclooxygenase-2 (COX-2) with analgesic-antiinflammatory activity. 83rd Canadian Society for Chemistry Conference 2000 (CSC), Calgary, Alberta, Canada. 29) P. N. Praveen Rao, Edward E. Knaus. Novel 1,1-dihalo-2,3-diarylcyclopropanes as a novel class of
selective cyclooxygenase-2 (COX-2) inhibitors. Faculty of Pharmacy and Pharmaceutical Sciences-Research Day 2000, University of Alberta, Edmonton, Canada. 30) P. N. Praveen Rao, Edward E. Knaus. Design & synthesis of 1,1-dihalo-2,3-diarylcyclopropanes as
selective cyclooxygenase-2 inhibitors with antiinflammatory & analgesic activity. Research revelations 2000, University of Alberta, Edmonton, Canada. 31) Mahadev Rao, P. N. Praveen Rao, M. N. A. Rao. Relative effectiveness of selenium, L (+) methionine &
selenomethionine against cisplatin induced nephrotoxicity. 50th Indian Pharmaceutical Congress & 17th Asian Congress of Pharmaceutical Sciences, 1998, Bombay, India. 32) P. N. Praveen Rao, Venkatesan P, Mahadev Rao, M.N.A. Rao. 2,2`azinobis-(3-ethylbenzthiazoline)-6-
sulfonic acid (ABTS) scavenging by some styrylketones. Third National Conference on trends in Drugs & Pharmaceutical Research- Global Scenario 1998, Manipal, India.

Source: http://sciencearchive.uwaterloo.ca/~nekkar/publications/documents/Clickhereforacompletelist.pdf