S PIG CHAT L E T T E R Volume 12 No 8 - Aug 31, 2009
From the office of George R. Charbonneau DVM & Steven D Wolfgram DVM
You should not have eaten, drunk, or smoked anythingin at least the previous fifteen to twenty minutes before
Barn Entry Requirements:
taking your temperature. Body temperature normally
"No Fever Please!"
fluctuates during the day, with the lowest levels around4 a.m. after sleeping and the highest around 6 p.m. after
We have all seen images of public health staff stationed at
a day of activity. Normal body temperature may differ
airports and borders where they are checking people for
as much as 0.6 EC (1 EF) between individuals or from
fever. Absence of a fever is an important criteria to use in
day to day within individuals. In women, temperature
determining who is at risk of spreading disease. As we fine
differs at various points in the menstrual cycle. The
tune our ability to keep nH1N1 out of our pig herds, we
measurement of fever in the arm pit and ear tend to be
should review how absence of fever can be used as an
more variable. Elderly patients may have a decreased
important criteria in determining who should or should not
ability to generate body heat during a fever, so even a
low-grade fever can have serious underlying causes in
Fever is a clinical sign that is associated with human
geriatric cases. If you have a fever then you should not go to
influenza but is not associated with the common cold. The
work. If you take your temperature when you are not
normal human body temperature measured by an oral
sick it will help to develop a baseline for your own
thermometer is 36.8 ± 0.7 EC (98.2 ± 1.3 EF). This means that
any oral temperature between 36.1 and 37.5 EC (96.9 and
Swine workers should keep a thermometer at home. If
99.5 EF) is a normal temperature. Fever is the term used to
you are unsure about whether you should or should not
describe a clinical sign where body temperatures are above
go to work take your temperature. This will make it
normal. Fever occurs when the body's thermoregulatory set-
easier to decide if you have a fever. Some advice for
point is elevated by about 1–2 EC (1.8-3.6 EF). A feverish
the kids. If mom or dad sometimes take your rectal
individual experiences the "chills" despite having an
temperature and sometimes take an oral temperature but
increased body temperature. Increased heart rate, muscle tone
you can only find one thermometer in the house; you
and shivering are caused by the body's attempts to reach the
need to have a serious conversation about getting an
new thermoregulatory set-point. Fever is usually
accompanied by lethargy, depression, loss of appetite,sleepiness, aches and the inability to concentrate. Fever
differs from hyperthermia, in that hyperthermia is an increasein body temperature over the body's thermoregulatory set-
Fall Thermometer Promotion
point, due to excessive heat production or insufficient heatremoval or both. eg. vigorous exercise in a warmenvironment. A fever is just one of many immunemechanisms that are used to neutralize a perceived threatinside the body, be it bacterial or viral.
< Fever - Anal - temperature is over 37.8 EC (100.0 EF)
< Fever - Oral - temperature is over 37.5 EC ( 99.5 EF) < Fever - Arm Pit - temperature is over 37.2 EC ( 99.0 EF)< Fever - Ear - temperature is over 37.2 ºC ( 99.0 ºF)
The values given are for an otherwise healthy, non-fasting
adult, dressed comfortably, indoors, in a room that is kept at
a normal room temperature (22.7 to 24.4 EC or 73 to 76 EF),
during the morning, but not shortly after arising from sleep.
The pH of the individual stock solutions ranged from 3.1
Mixing Water Medications:
to 10.5. The percent of reactions ranged from 0 up to53% (Figure 1). When the individual solutions were
Bad Things Can Happen!
mixed in acidic water (citric acid), reactions occurred
It is common practice in swine barns to have medicators
with ASA, amoxicillin, trimethoprim-sulfamethoxazole,
set up for the distribution of antibiotics, vaccines,
potassium penicillin and sulfamethazine. The
electrolytes and/or other compounds. On occasion it may
tetracyclines, tetracyline combinations and tiamulin
be desirable to administer more than one substance in
reacted when mixed in alkaline water (ammonia).
succession or even at the same time. When administeringwater medications, we make several assumptions;
This study shows why flushing of water lines and
< that the medication reaches all pigs;
medicators between treatments is important. It is also
< that all pigs consume the medication; t
important to consider what water additives (eg.
acidifiers) are in the water on a routine basis and whether
< that the water delivery system is functional;
they should be discontinued prior to starting a new course
< that the medicator delivers the proper concentration
Reference: Dorr PM, Madson D, Wayne S, et al. Impact of pH
In this study, the researchers wanted to look at the
modifiers and drug exposure on the solubility of pharmaceuticalproducts commonly administered through water delivery systems.
solubility of pharmaceutical products when mixed with
J Swine Health Prod. 2009;17(4):217-222.
other water additives. Fifteen water soluble medications,including acetylsalicylic acid (ASA-aspirin), amoxicillin,
potassium penicillin, lincomycin, neomycin, tetracycline,sulfamethazine, trimethoprim-sulfamethoxazole andtiamulin were examined. Medications were observed for
Timing of Enterisol Ileitis Vaccination
stability and pH in stock solution mixed according to
Vaccination timing is important for all vaccine
label directions using distilled water, and then for
applications. Enterisol Ileitis vaccine seems to present
stability when mixed with other medications, with citric
challenges about the correct placement of the
vaccination. The uncertainty usually centers on how tocalculate when is the right time to vaccinate. Propertiming of ileitis vaccination is essential for the best
protection of pigs against ileitis. Once the time between
Chlortet Tiamulin
exposure and development of antibodies is understoodthen correct placement of ileitis vaccine for the best
protection of pigs against ileitis can be achieved.
Like many other vaccines, it takes about 3-4 weeks after
vaccination for protection against Lawsonia intra-cellularis, the organism that causes ileitis, to develop. This lag period of 3-4 weeks is known as the “onset ofimmunity”, and allows the pig’s immune system to
respond to the vaccine and develop protective immunityso that when the pig is subsequently exposed to the
virulent field bacterium, it is protected against
How to Calculate Vaccination Time: Several studies have
documented ileitis vaccination protects pigs through tothe end of the finisher. This is true for pigs vaccinated at
Figure 1. Formation of Precipitates X denotes precipitate
weaning or at any stage in the nursery or beyond. The
vaccination, however, has to be done at least 3-4 weeksprior to anticipated infection with L. intracellularis sothat protective immunity is present when pigs are first
exposed to infection (the “onset of immunity” lag
Farmers Encouraged To Take
period). Seroconversion usually occurs 2-4 weeks or later
Advantage of Free Disposal of Expired
post-infection (the “diagnostic indicator” lag period). Using seroconversion as a means of estimating when
Products And Sharps
vaccination should occur requires that both lag periods
A well established obsolete pesticide collection program
be added together in order for vaccination to be placed
is being expanded this year to also provide safe disposal
sufficiently ahead of the infection indicator
for unused animal health products and sharps. As part of
(seroconversion). In general, vaccination should be
this project, farmers will be able to bring their obsolete
placed at least 6-8 weeks prior to anticipated
pesticides, unused animal health products and used
sharps (needles, syringes and scalpel blades) to a series
diagnostic profiling to accurately identify proper vaccination timing,
of 16 collections sites across the province for safe and
a recommended “default” time frame for Lawsonia vaccination is
environmentally responsible disposal October 20 - 22,
during the mid-to-late nursery phase (6-10 weeks of age) in typicalNorth American pork production systems.
Unused animal health products should have a label that
Another, less precise indicator that can be used in the
contains a Drug Identification Number (DIN). Animalbiologicals are regulated in a different manner and will
not have a DIN but are still acceptable. These productswill say “vaccine, bacterin, toxoid, antitoxin, antibody ordiagnostic” on them. They will have a Serial Number onthe label rather than a DIN.
Medicated Feed will not be accepted. Premise
Figure 1: Identifying the Target Window for Vaccination
disinfectants, pesticides and animal health products thatare in aerosol containers will not be accepted. They will
absence of diagnostics is the historical time of first
also not accept any household or human use items.
appearance of clinical signs in a particular herd. Clinical
Sharps must be brought in a closed container. Ziploc
signs usually appear 2-3 weeks after exposure to the
bags and loose sharps are not acceptable. (Needles
Lawsonia bacterium, so roughly about the same time that
should not be able to poke through the container).
seroconversin occurs. This being the case, using clinicalsigns as the indicator proper vaccination timing would
The program will run from Tuesday October 20 to
also be 6-8 weeks prior to the expected time of first
Thursday October 22 at the following locations during
their respective business hours:< Ailsa Craig: Hensall District Co-Operative
Adjustments in timing may need to be made periodically
based upon potential changes in infection dynamics and
observed responses to vaccination on individual farms.
< Harriston: North Wellington Co-operative Services
< Jordan Station: Vineland Growers Co-operative
Additional information is available on the AgCare orOntario Farm Animal Council websites: www.agcare.orgor www.ofac.org or contact the Ontario Ministry ofAgriculture Food & Rural Affairs at 877-424-1300.
COMUNE DI ALBIGNASEGO Verbale di deliberazione della Giunta Comunale N. 19 del 27/01/2000 L'anno duemila , addì ventisette del mese di gennaio , alle ore 18,20 , nella Residenza Municipale di Villa Obizzi , si è riunita sotto la presidenza del Sindaco Lanfranco Casale la Giunta Comunale. Partecipa all'adunanza ed è incaricato della redazione del presente verbale Il Segret
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