Safety Data Sheet Tetracycline 1. PRODUCT AND COMPANY IDENTIFICATION Product Name: Tetracycline
Synonyms/Generic Names: 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12aoctahydro-3,6,10,12,12a- pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide hydrochloride SDS Number: 753.00 Product Use: For Educational Use Only Manufacturer: Columbus Chemical Industries, Inc.
For More Information Contact: Ward's Science
5100 West Henrietta Rd. PO Box 92912-9012 Rochester, NY 14692
(800) 962-2660 (Monday-Friday 7:30-7:00 Eastern Time)
In Case of Emergency Call: CHEMTREC - 800-424-9300 or 703-527-3887 (24 Hours/Day, 7 Days/Week) 2. HAZARDS IDENTIFICATION OSHA Hazards: Target organ effect, Irritant Target Organs: Liver, Teeth, Bone Signal Word: Warning Pictograms: GHS Classification:
Specific target organ toxicity - single exposure
GHS Label Elements, including precautionary statements:
Hazard Statements: Precautionary Statements:
Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray.
Wear protective gloves/ eye protection/ face protection.
IF ON SKIN: Wash with plenty of soap and water.
IF INHALED: Remove victim to fresh air and keep at rest in a position
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact
lenses, if present and easy to do. Continue rinsing.
Potential Health Effects Inhalation
May be harmful if inhaled. Causes respiratory tract irritation.
May be harmful if absorbed through skin. Causes skin irritation.
Ingestion NFPA Ratings HMIS Ratings Flammability Reactivity Reactivity Specific hazard Personal
3. COMPOSITION/INFORMATION ON INGREDIENTS
EINECS# / Molecular Component
C22H24N2O8 · HCl 4. FIRST-AID MEASURES
Rinse with plenty of water for at least 15 minutes and seek medical attention if necessary.
Move casualty to fresh air and keep at rest. If breathing is difficult, give oxygen. If not breathing, give artificial respiration. Get medical attention if necessary.
Flush with plenty of water and wash using soap. Get medical attention if necessary.
Ingestion Do Not Induce Vomiting! Never give anything by mouth to an unconscious person. If conscious, wash out mouth with water. Get medical attention if necessary. 5. FIRE-FIGHTING MEASURES
Suitable (and unsuitable)
Product is not flammable. Use appropriate media for adjacent fire. Cool
extinguishing media Special protective equipment
Wear self-contained, approved breathing apparatus and full protective
and precautions for firefighters
clothing, including eye protection and boots.
Specific hazards arising from
Emits toxic fumes (carbon oxides, hydrogen chloride gas, nitrogen
oxides) under fire conditions. (See also Stability and Reactivity section).
6. ACCIDENTAL RELEASE MEASURES
See section 8 for recommendations on the use of personal protective
protective equipment and emergency procedures Environmental precautions
Prevent spillage from entering drains. Any release to the environment may be subject to federal/national or local reporting requirements.
Methods and materials for
Pick up and arrange disposal without creating dust. Sweep up and place
containment and cleaning up
in suitable, closed containers for disposal. Clean surfaces thoroughly with water to remove residual contamination. Dispose of all waste and cleanup materials in accordance with regulations.
7. HANDLING AND STORAGE Precautions for safe handling See section 8 for recommendations on the use of personal protective equipment. Use with adequate ventilation. Wash thoroughly after using. Keep container closed when not in use. Avoid formation of dusts. Conditions for safe storage, including any incompatibilities Store in cool, dry well ventilated area. Keep away from incompatible materials (see section 10 for incompatibilities). 8. EXPOSURE CONTROLS / PERSONAL PROTECTION Occupational exposure controls: Contains no substances with occupational exposure limit values. Personal Protection
Wear chemical safety glasses or goggles.
Provide local exhaust, preferably mechanical. If exposure levels are excessive, use an approved respirator.
Wear nitrile or rubber gloves, apron or lab coat.
Other Recommendations Provide eyewash stations, quick-drench showers and washing facilities accessible to areas of use and handling. 9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance (physical state, color, etc.)
Upper/lower flammability or explosive limit
10. STABILITY AND REACTIVITY
Chemical Stability Possibility of Hazardous Reactions Conditions to Avoid Incompatible Materials Hazardous Decomposition Products
Carbon oxides, nitrogen oxides, hydrogen chloride gas.
11. TOXICOLOGICAL INFORMATION Acute Toxicity Respiratory Ingestion Carcinogenicity
No components of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
No components of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by ACGIH.
No components of this product present at levels greater than or equal to 0.1% is identified as a known or anticipated carcinogen by NTP.
No components of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by OSHA.
Signs & Symptoms of Exposure
Irritation, redness, watering eyes, itchiness.
Irritation, nausea, vomiting, diarrhea, phototoxic reactions, yellowing of teeth, reduced mineralization.
The substance is toxic to the reproductive system, liver.
Teratogenicity Mutagenicity Embryotoxicity Specific Target Organ Toxicity
Inhalation - May cause respiratory irritation.
Reproductive Toxicity Respiratory/Skin Sensitization
Prolonged or repeated exposure may cause allergic reactions in certain sensitive individuals.
12. ECOLOGICAL INFORMATION Ecotoxicity Aquatic Vertebrate
LC50 - Salvelinus namaycush - 220 mg/l - 96 h
Aquatic Invertebrate Not Available Terrestrial Persistence and Degradability Bioaccumulative Potential Mobility in Soil PBT and vPvB Assessment Other Adverse Effects 13. DISPOSAL CONSIDERATIONS
Users should review their operations in terms of the applicable federal/national or
local regulations and consult with appropriate regulatory agencies if necessary before disposing of waste products or residues.
Users should review their operations in terms of the applicable federal/national or
local regulations and consult with appropriate regulatory agencies if necessary before disposing of waste product container.
The information offered in section 13 is for the product as shipped. Use and/or alterations to the product may significantly change the characteristics of the material and alter the waste classification and proper disposal methods. 14. TRANSPORTATION INFORMATION
15. REGULATORY INFORMATION
All ingredients are listed on the TSCA inventory.
All ingredients are listed on the DSCL inventory.
Class D-2A: Material causing other toxic effects (VERY TOXIC).
16. OTHER INFORMATION
Disclaimer: Columbus Chemical Industries, Inc. (“Columbus”) believes that the information herein is factual but is not intended to be all inclusive. The information relates only to the specific material designated and does not relate to its use in combination with other
materials or its use as to any particular process. Because safety standards and regulations are subject to change and because Columbus has no continuing control over the material, those handling, storing or using the material should satisfy themselves that they have current
information regarding the particular way the material is handled, stored or used and that the same is done in accordance with federal, state and local law. COLUMBUS MAKES NO WARRANTY, EXPRESS OR IMPLIED, INCLUDING (WITHOUT LIMITATION)
WARRANTIES WITH RESPECT TO THE COMPLETENESS OR CONTINUING ACCURACY OF THE INFORMATION CONTAINED HEREIN OR WITH RESPECT TO FITNESS FOR ANY PARTICULAR USE.
SHAKTI PRANA -CELEBRATE YOUR INNER FLOW mit HP Helen Levant & LSB Karin Roth Retreat 18.- 20. Oktober 2013 / Seminarhaus Die Lichtung IN WO Shakti ist das Sinnbild für schöpferische Kraft, göttliche Weiblichkeit und die Manifestation wahren Reichtums. Shakti Energie ist fein, verbunden mit Schönheit, Intuition und Weisheit. Der weibliche Körper unterliegt aus yogischer Sicht b
Anne-Marie Lizin Bericht über Guantánamo1 Einführung Auf ihrer Rotterdamer Jahrestagung im Juli 2003 hob die Parlamentarische Versammlung der OSZE (OSZE PV) besonders hervor, dass die Bekämpfung von Terrorismus mit demokratischen Werten und der Achtung der Men-schenrechte in Einklang zu bringen sei. In ihrer dort verabschiedeten „Ent-schließung über die von den Vereinigten Staaten am