Tadalafil zeichnet sich durch eine außergewöhnlich lange Halbwertszeit im Vergleich zu anderen PDE5-Inhibitoren aus. Diese pharmakokinetische Eigenschaft führt zu einer verlängerten Exposition des Wirkstoffs im Organismus. Die Eliminationsrate hängt von der hepatischen Aktivität des CYP3A4-Enzyms ab. Lipophile Eigenschaften unterstützen eine weite Verteilung in unterschiedlichen Geweben. Eine ausgeprägte Stabilität gegenüber Nahrungsaufnahme macht den Stoff besonders konstant in seiner Wirkung. Unter generischen Präparaten wird cialis online häufig mit einem vergleichbaren pharmakologischen Profil beschrieben.

Medicare tier 4 comprehensive - 2008

Tier Requirements/
Medicare Tier 4 Comprehensive - 2008

ANALGESICS
NSAIDs
diclofenac sodium delayed-rel Tier COX-2 Inhibitors
Gout
Narcotic Analgesics
Narcotic Analgesics, CII
morphine sulfate immediate release Tier Tier Requirements/
Non-narcotic Analgesics

ANESTHETICS
Local Anesthetics

ANTI-INFECTIVES
Antibacterials
CEFUROXIME SODIUM/DEXTROSE inj 750 mg Tier Requirements/
AUGMENTIN chewable tabs 125 mg, 250 mg doxycycline hyclate caps, tabs Tier Tier Requirements/
Antifungals
Antimalarials
Antiretroviral Agents
Tier Requirements/
Non-nucleoside Reverse Transcriptase Inhibitors Nucleoside Reverse Transcriptase Inhibitors Nucleotide Reverse Transcriptase Inhibitors Antitubercular Agents
Antivirals
Tier Requirements/
QL: Tamiflu caps (30 mg) - 20 caps per 180 days Tamiflu caps (45 mg, 75 mg) - 10 caps per 180 days Miscellaneous
sulfamethoxazole/trimethoprim Tier sulfamethoxazole/trimethoprim inj Tier Requirements/
QL: Alinia tabs - 6 tabs per 25 days Alinia susp - 60 mL per 25 days
ANTINEOPLASTIC AGENTS
Hormonal Antineoplastic Agents
Luteinizing Hormone-releasing Hormone (LHRH) Agonists Injectable Agents
Tier Requirements/
Tier Requirements/
Oral Agents
Tier Requirements/
Protective Agents

CARDIOVASCULAR
ACE Inhibitors
ACE Inhibitor/Calcium Channel Blocker Combinations
ACE Inhibitor/Diuretic Combinations
benazepril/hydrochlorothiazide Tier Tier Requirements/
Adrenolytics, Central
Aldosterone Receptor Antagonists
Alpha Blockers
Angiotensin II Receptor Antagonists/Combinations
Antiarrhythmics
quinidine gluconate ext-rel 324 mg Tier Requirements/
Antilipemics
Beta-blockers
Tier Requirements/
Beta-blocker/Diuretic Combinations
Calcium Channel Blockers
Calcium Channel Blocker/Antilipemic Combinations
Digitalis Glycosides
Direct Renin Inhibitors
Diuretics
spironolactone/hydrochlorothiazide Tier Requirements/
Endothelin Receptor Antagonists
Nitrates
isosorbide dinitrate ext-rel tabs Tier Miscellaneous

CENTRAL NERVOUS SYSTEM
Antianxiety
Anticonvulsants
Tier Requirements/
lamotrigine chewable dispersible tabs QL: gabapentin caps and tabs - 3600 mg/day per 25 days Neurontin oral soln - 1880 mg/day per 25 days Antidementia
Antidepressants
Tier Requirements/
Selective Serotonin Reuptake Inhibitors (SSRIs) Serotonin Norepinephrine Reuptake Inhibitors (SNRIs)*
* Indicates the proposed mechanism of action, based on the American
Psychiatric Association Summary of Treatment Recommendations.
Antiparkinsonian Agents
Tier Requirements/
Antipsychotics
Attention Deficit Hyperactivity Disorder
Tier Requirements/
Hypnotics
Migraine
QL: Frova - 9 tabs per 25 days Imitrex inj - 5 inj per 25 days Imitrex kits - 2 kits per 25 days Imitrex spray 5 mg - 12 doses per 25 days Imitrex spray 20 mg - 6 doses per 25 days Maxalt/Maxalt-MLT - 12 tabs per 25 days Relpax - 12 tabs per 25 days Zomig/Zomig-ZMT tabs - 6 tabs per 25 days Mood Stabilizers
Tier Requirements/
Multiple Sclerosis Agents
Musculoskeletal Therapy Agents
Narcolepsy/Cataplexy
Psychotherapeutic-Miscellaneous
Miscellaneous
Tier Requirements/
ENDOCRINE AND METABOLIC
Androgens
Antidiabetics
Dipeptidyl Peptidase-4 (DPP-4) Inhibitors Dipeptidyl Peptidase-4 (DPP-4) Inhibitor/Biguanide Combinations Tier Requirements/
Insulin Sensitizer/Biguanide Combinations Insulin Sensitizer/Sulfonylurea Combinations Bisphosphonates
Calcitonins
Calcium Receptor Antagonists
Chelating Agents
Tier Requirements/
Contraceptives
norethindrone acetate/EE/iron 1/20 levonorgestrel/EE 0.15/30 - Levora norethindrone acetate/EE/iron 1.5/30 norgestrel/EE 0.3/30 - Low-Ogestrel levonorgestrel/EE 0.15/30 - Quasense Tier ethynodiol diacetate/EE 1/35 - Zovia 1/35 Tier ethynodiol diacetate/EE 1/50 - Zovia 1/50 Tier Tier Requirements/
medroxyprogesterone acetate 150 mg/mL Tier Endometriosis
Enzyme Replacements
Estrogens
Tier Requirements/
Estrogen/Progestins
Glucocorticoids
methylprednisolone sodium succinate inj Glucose Elevating Agents
Human Growth Hormones
Tier Requirements/
Parathyroid Hormones
Phosphate Binder Agents
Progestins
Selective Estrogen Receptor Modulators
Thyroid Agents
Vasopressins
Miscellaneous
Tier Requirements/
GASTROINTESTINAL
Antidiarrheals
Antiemetics
trimethobenzamide caps 300 mg Tier Emend (Trifold Pack) - 2 packs per 25 days Marinol - 60 caps per 25 days ondansetron (4 mg, 8 mg) - 18 tabs per 25 days Ondansetron (24 mg) - 2 tabs per 25 days ondansetron (2 mg/mL) inj - 10 mL per 25 days ondansetron (32 mg/50 mL) inj - 50 mL per 25 days ondansetron oral soln - 100 mL per 25 days Ondansetron/NaCl (32 mg/50 mL) inj - 50 mL per 25 days Antispasmodics
Tier Requirements/
Cholelitholytics
H2-Receptor Antagonists
Inflammatory Bowel Disease
Irritable Bowel Syndrome
Laxatives
Pancreatic Enzymes
Tier Requirements/
Prostaglandins
Proton Pump Inhibitors
Proton Pump Inhibitor/Anti-infective Combinations
Saliva Stimulants
Steroids, Rectal
Miscellaneous

GENITOURINARY
Benign Prostatic Hyperplasia
Urinary Antispasmodics
Tier Requirements/
Vaginal Anti-infectives
Miscellaneous

HEMATOLOGIC
Anticoagulants
Hematopoietic Growth Factors
Platelet Aggregation Inhibitors
Platelet Synthesis Inhibitors
Tier Requirements/
Miscellaneous

IMMUNOLOGIC AGENTS
Disease-modifying Antirheumatic Drugs (DMARDs)
Immunoglobulins
Immunomodulators
Immunosuppressants
Tier Requirements/
Vaccines
PERTUSSIS, and HAEMOPHILUS B CONJUGATE VACCINE HAEMOPHILUS B CONJUGATE and HEPATITIS B Tier 2 MEASLES and RUBELLA VIRUS VACCINE (LIVE) Tier Requirements/
NUTRITIONAL/SUPPLEMENTS
Electrolytes
sodium polystyrene sulfonate Tier Vitamins
Miscellaneous

RESPIRATORY
Anaphylaxis Treatment Agents
Anticholinergics
QL: Atrovent HFA - 2 inhalers per 25 days Anticholinergic/Beta Agonist Combinations
QL: Combivent - 2 inhalers per 25 days ipratropium/albuterol Tier Requirements/
Antihistamines, Low/Nonsedating
Antihistamines, Sedating
Antihistamine/Decongestant Combinations
Beta Agonists
QL: albuterol ampules - 300 mL per 25 days albuterol inhaler - 2 inhalers per 25 days Foradil - 60 caps per 25 days Maxair - 1 inhaler per 25 days Proair HFA - 2 inhalers per 25 days Proventil HFA - 2 inhalers per 25 days Tier Requirements/
Cystic Fibrosis
Leukotriene Receptor Antagonists
Mast Cell Stabilizers
QL: cromolyn ampules - 240 mL per 25 days Nasal Steroids
QL: flunisolide spray - 2 inhalers per 25 days fluticasone spray - 1 inhaler per 25 days Nasacort AQ - 1 inhaler per 25 days Steroid/Beta Agonist Combinations
Steroid Inhalants
Pulmicort Flexhaler (90 mcg) - 4 inhalers per 25 days Pulmicort Flexhaler (180 mcg) - 2 inhalers per 25 days Pulmicort Respules - 60 Respules per 25 days Pulmicort Turbuhaler - 2 inhalers per 25 days Tier Requirements/
Xanthines
Miscellaneous
Dermatology
clindamycin gel, lotion, soln Tier Tier Requirements/
alclometasone crm, oint 0.05% Tier fluocinolone acetonide soln 0.01% Tier hydrocortisone crm, lotion, oint 2.5% Tier Requirements/
betamethasone valerate crm, lotion, oint 0.1% Tier fluocinolone acetonide crm, oint 0.025% fluticasone propionate crm 0.05%, oint 0.005% Tier 1 hydrocortisone butyrate crm, oint, soln 0.1% hydrocortisone valerate crm, oint 0.2% mometasone crm, lotion, oint 0.1% Tier triamcinolone acetonide crm, lotion, triamcinolone acetonide crm, lotion, oint 0.1% betamethasone dipropionate augmented crm, betamethasone dipropionate crm, lotion, desoximetasone crm, oint 0.25%, gel 0.05% fluocinonide crm, gel, oint, soln 0.05% triamcinolone acetonide crm, oint 0.5% Tier betamethasone dipropionate augmented gel, clobetasol propionate crm, foam, oint 0.05% halobetasol propionate crm, oint 0.05% Tier Requirements/
metronidazole crm, gel, lotion Tier Mouth/Throat/Dental Agents
Ophthalmic
Tier Requirements/
sulfacetamide oint, soln 10% Tier Anti-infective/Anti-inflammatory Combinations neomycin/polymyxin B/dexamethasone neomycin/polymyxin B/hydrocortisone sulfacetamide/prednisolone phosphate Tier Requirements/
Carbonic Anhydrase Inhibitor/Beta-blocker Combinations Sympathomimetic/Beta-blocker Combinations Otic
Anti-infective/Anti-inflammatory Combinations neomycin/polymyxin B/hydrocortisone Tier Tier Requirements/
fluocinolone acetonide crm, oint 0.025% . 43 fluocinonide crm, gel, oint, soln 0.05% . 43 hydrocortisone crm, lotion, oint 2.5% . 42 hydrocortisone valerate crm, oint 0.2%. 43 halobetasol propionate crm, oint 0.05%.43 levonorgestrel/EE 0.15/30 - Quasense . 28 methylprednisolone sodium succinate inj. 30 triamcinolone acetonide crm, oint 0.5% . 43

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