Material Safety Data Sheet Issued Date 09-Aug-2007 Revision Date 04-Jan-2011 Revision Number: 8 Emergency Telephone Number
Chemtrec: (800) 424-9300 (24hrs) or (703) 527-3887
Medical: Rocky Mountain Poison Control Center
Company Information Contact Information Phone Number Available Hrs Product Name Recommended Use Product Code Emergency Overview
May cause irritation to the respiratory tract.
CAUTION Appearance Light, Tan. Physical State Granular. Odor Sweet. Musty. Potential Health Effects Eyes _____________________________________________________________________________________________ 12U-144 - TriCor DF
3. COMPOSITION/INFORMATION ON INGREDIENTS
Ingredients Name Chemical Name Eye Contact
Hold eye open and rinse slowly and gently with water for 15 - 20 minutes. Remove contact lenses, if present, after 5 minutes, then continue rinsing eye. Call a poison control center or doctor for treatment advice. Skin Contact
Take off contaminated clothing. Rinse skin immediately with plenty of water for 15-20 minutes. Call poison control center or doctor for treatment advice. Inhalation
Move person to fresh air. If person is not breathing, call 911 or an ambulance, then give artifical respiration. Call a physician or Poison Control Centre immediately
Call a physician or Poison Control Center immediatelyHave person sip a glass of water if able to swallowNever give anything by mouth to an unconscious personDo not induce vomiting unless told to do so by a poison control center or doctor
Notes to Physician
No information availableTreat symptomatically
Flammable Explosive Properties Flash Point Autoignition Temperature Flammability Limits in Air Extnguishing Media Fire/Explosion Hazard
Dust clouds generated during handling and/or storage can form explosive mixtures with air. Dust explosion characteristics vary with the particle size, particle shape, moisture content, contaminants, and other variables. _____________________________________________________________________________________________ 12U-144 - TriCor DF
Hazardous Combustion Products
Dust clouds generated during handling and/or storage can form explosive mixtures with air. Dust explosion characteristics vary with the particle size, particle shape, moisture content, contaminants, and other variables.
As with any dry material, pouring this material or allowing it to free fall or be conveyed through chutes or pipes can accumulate and generate electrostatic sparks, potentially causing ignition of the material itself, or any flammable materials which may come into contacft with the material or its contianer. Check that all equipment is properly grounded and installed to satisfy electrical classification requirements. , Carbon dioxide (CO2), Sulfur oxides, Methyl mercaptan, Amines.
Flammability 0 1 Instability - Personal Precautions
Avoid contact with the skin and the eyes.
Consult a regulatory specialist to determine appropriate state or local reporting requirements, for assistance in waste characterization and/or hazardous waste disposal and other requirements listed in pertinenet environmental permits.
Methods for Clean-up
Sweep up and shovel into suitable containers for disposal.
Keep out of reach of children. Ensure adequate ventilation. Fine dust dispersed in air may ignite.
8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Exposure Guidelines Chemical Name ACGIH TLV _____________________________________________________________________________________________ 12U-144 - TriCor DF
Chemical Name ACGIH TLV Engineering Controls
Investigate engineering techniques to reduce exposures. Local mechanical exhaust ventilation is preferred. Consult ACGIH ventilation manual or NFPA Standard 91 for design of exhaust systems. .
PESTICIDE APPLICATORS & WORKERS. THESE WORKERS MUST REFER TO PRODUCT LABELING AND DIRECTIONS FOR USE IN ACCORDANCE WITH EPA WORKER PROTECTION STANDARD 40 CFR PART 170.
Personal Protective Equipment Eye/face Protection
Eye contact should be avoided through the use of chemical safety glasses, goggles, or a faceshield selected in regard to exposure potential.
Wear protective gloves/clothing. Socks and footwear.
Where airborne exposure is likely, use NIOSH approved respiratory protection equipment appropriate to the material and/or its components. Full facepiece equipment is recommended and, if used, replaces need for face shield and/or chemical goggles. If exposures cannot be kept at a minimum with engineering controls, consult respirator manufacturer to determine appropriate type equipment for given application. Observe respirator use limitations specified by NIOSH or the manufacturer. For emergency and other conditions where there may be a potential for significant exposure, use an approved full face positive-pressure, self-contained breathing apparatus. Respiratory protection programs must comply with 29 CFR 1910.134. .
General Hygiene Considerations Do not eat, drink or smoke when using this product. Wash hands and face before breaks and immediately after handling the product. Remove and wash contaminated clothing before re-use. Appearance Physical State Boiling Point/Range Melting Point/Range Specific Gravity Solubility Evaporation Rate Vapor Pressure Vapor Density VOC Content Viscosity Molecular Weight Bulk Density Percent Solids Percent Volatiles Stability Conditions to Avoid Incompatible Materials Hazardous Decomposition Products
Carbon dioxide (CO2). Oxides of sulfur. Amines. Methyl mercaptans.
Possibility of Hazardous Polymerization _____________________________________________________________________________________________ 12U-144 - TriCor DF
Acute Toxicity Product Information TriCor DF- Acute oral LD50 rat = 2379 mg/kg (male) 2794 mg/kg (female) Acute dermal LD50 rabbit = >5,000 mg/kg Eye - rabbit = Minimal irritation to the conjunctiva was observed with all irritation resolving witin 4 days. Skin effects- rabbit = Not a dermal irritant Metribuzin - In a three week dermal toxicity study, rabbits were treated with metribuzin at doses of 40, 200, and 1000 mg/kg for 6 hr/dy, 5 dys/wk. The high dose evidence of increased cholesterol levels and liver enzyme function was noted. Thyroxine levels were increased at doses of 200 mg/kg and above. All of these effects were slight and reversible. The NOEL was 40 mg/kg. In subacute inhalation studies, rats were exposed to aerosol concentrations of metribuzin ranging from 31 to 745 mg/cubic meter for 6 hr/dy, 5 dys/wk, for 3 weeks. Effects observed included behavioral changes, decreased body weight gains, liver enzyme induction and organ weight effects. The NOEC was 31 mg/cubic meter. Oral LD50 (rat) = 2,194 mg/kg Dermal LD50 (rat) = >5,000 mg/kg Inhalation LC50 (4 hr rat) = 0.709 mg/L Chronic Toxicity
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Metribuzin - Dogs were administered metribuzin for 2 years at dietary concentrations of 25, 100 and 1500 ppm. Effects observed at high concentration included decreases in body weight and food consumption, anemia, liver effects, kidney effects, testicular effects and mortality. The NOEL was 100 ppm.
In 2 year dietary studies with rats, concentrations ranging from 25 to 900 ppm were adminstered. At concentrations of 300 ppm and greater, effects observed included decreased body weight gains, increased thyroid weights and changes in thyroid hormones. At 900 ppm, there was an increased incidence of follicular hyperplasia seen in the thyroid. The systemic NOEL was 30 ppm. .
Metribuzin carcinogenicity - Metribuzin was investigated for carcinogenicity in chronic feeding studies using rats and mice at maximum levels of 900 and 3200 ppm, respectively. There was no evidence of carcinogenic potential observed in either species.
Mutagenicity - Metribuzin is not gentoxic
Developmental toxicity - In rat teratology studies, metribuzin was administered orally during gestation at doses of 25, 70, or 200 mg/kg. Maternal toxic effects were observed at all doses. At 200 mg/kg fetotoxic effects observed included reduced median placental weights, reduced median fetal weights, and increased incidence of delayed ossification. Teratogenic effects were not observed at any of the doses tested. The NOEL's for maternal and developmental toxicity were less than 25 and 70 mg/kg, respectively. When rabbits were administered metribuzin by oral gavage during gestation at doses of 10, 30, or 85 mg/kg, there was no evidence of any developmental effects. The NOEL's for maternal and developmental toxicity were 30 and 85 mg/kg respectively.
Reproduction - In a rat reproduction study, metribuzin was administered for 2 generations at dietary concentrations of 30, 150 or 750 ppm. Offspring at the high dose exhibited reduced body weight gains starting at day 14 lactation, an age correlating with the consumption of treated diets. The NOEL's for materials and reproductive toxicity were 30 and 750 ppm, respectively. .
Metribuzin - can travel (seep or leach) through soil and can comtaminate ground water which may be used as drinking water. .
Waste Disposal Method
Pesticide wastes are acutely hazardous. Improper disposal of excess pesticide or rinsate is a violation of Federal law. If the wastes cannot be disposed of by use or according to label instructions, contact your State Pesticide or Environmental Control Agency, or the Hazardous Waste representative at the nearest EPA Regional Office for guidance. .
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Non refillable container. Do not reuse this container. . (For plastic containers). Clean container promptly after emptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank and drain for 10 seconds after the flow begins to drip. Fill container 1/4 full with water and recap. Shake for 10 seconds. Pour rinsate into application requipment or a mix tank or store rinsate for later use or disposal. Drain for 10 seconds after the flow begins to drip. Repeat this procedure two more times. The offer for recycling if avilable or puncture and dipose of in a sanitary landfill, or by incineration, or, if allowed by state and local authorities, by burning. If burned, stay out of smoke. .
(For paper bags) . Completely empty bag into application equipment. Then offer for recycling if available or dispose of empty bag in a sanitary landfill or by incineration or, if allowed by state and local authorities, by burning. If burned, stay out of smoke. .
IMDG/IMO International Inventories Silicon dioxide EINECS/ELINCS EINECS/ELINCS USA Federal Regulations SARA 313 Y Chemical Name SARA 311/312 Hazardous Categorization
Chronic Health Hazard Acute Health Hazard _____________________________________________________________________________________________ 12U-144 - TriCor DF
Sudden Release of Pressure Hazard Reactive Clean Water Act Clean Air Act, Section 112 Hazardous Air Pollutants (HAPs) (see 40 CFR 61) This product does not contain any HAPs. CERCLA RCRA Pesticide Information State Regulations California Proposition 65 This product does not contain any Proposition 65 chemicals. State Right-to-Know Chemical Name Massachusetts New Jersey Pennsylvania Illinois Rhode Island International Regulations Mexico - Grade Chemical Name Category Carcinogen Status Exposure Limits This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all the information required by the CPR. WHMIS Hazard Class Not determined Revision Date Revision Summary Update section 13 Update section 8 _____________________________________________________________________________________________ 12U-144 - TriCor DF
UPI, Inc. believes that the information and recommendations container herein (including data and statements) are accurate as of the date hereof. NO WARRANTY OF FITNESS FOR ANY PARTICULAR PURPOSE, WARRANTY OF MERCHANTABILITY, OR ANY OTHER WARRANTY, EXPRESSED OR IMPLIED, IS MADE CONCERNING THE INFORMATION PROVIDED HEREIN. The information provided herein relates only to the specific product designated and may not be valid where such product is used in combination with other materials or in any process. Further, since the conditions and methods of use are beyond the control of UPI, Inc. UPI, Inc. expressly disclaims any and all liability as to any results obtained or arising from any use of the product or reliance on such information.
End of MSDS _____________________________________________________________________________________________
Neurodermitis im Kindesalter Die frühzeitige Therapie ist matchentscheidendMARC PLEIMES, PETER SCHMID-GRENDELMEIER, LISA WEIBEL, ZÜRICH Eine grundsätzliche Heilung der Veranlagung zur atopischen Derma- titis ist nicht möglich. Die genetische Disposition besteht lebenslang. Entgegen gängigen Vorstellungen bestehen weiterhin nur bei einem ekzematösen Entzündungsreaktionen.
Secretary: Joy Woodward P O Box 53219, Kenilworth 7745, South Africa. Editorial Team: Mick Dower with Coen Calitz, Johan Schoombee and John Winter (The views expressed in this publication do not necessarily reflect the views of the Cape Cliivia Club) The year end meeting was held at Kirstenbosch, followed by the traditional braai. Over a 100 members attended and enjoyed Johan Scho